Absorbed lead continuously adds to the lead deposited in the vascularized circumpulpal dentin of the teeth. Thus, this dental tissue is expected to contain a lead concentration which reflects the integrated lead exposure during the time from completion of tooth formation to tooth extraction or shedding. A method has been developed to assess the lead level in the dentin surrounding the pulp cham...

Supply chains are formed out of complex interactions amongst several enterprises whose aim is to produce and transport goods so that customer desired products are sold at various retail outlets. Computing the total average cycle time for customer orders entering such a complex network of systems is an important exercise. In this paper, we present analytical models for evaluating the average lea...

The aim of the study was to evaluate the immediate reproducibility of time domain parameters in the signal averaged electrocardiogram using a new method for endpoint determination in individual Frank leads. The method is based on a statistical model of the electrocardiogram (ECG) in which maximum likelihood (ML) estimation is employed. The reproducibility of the ML method was compared to that o...

The toxic metal lead is a widespread environmental health hazard that can adversely affect human health. In an effort to better understand the cellular and molecular consequences of lead exposure, we have employed cDNA microarrays to analyze the effects of acute lead exposure on large-scale gene expression patterns in immortalized rat astrocytes. Our studies identified many genes previously rep...

In this work, we study the problem of whether grant proposals lead academic publications in terms of generation of scientific ideas. This is an important computational social sciene question that can help us understand the dynamics of scientific innovation. We propose simple but scalable techniques for lead/lag estimation, based on LDA and time series analysis, that work on any unlabeled textua...

Shortening lead times in a business process is important for meetings service level agreements, decreasing inventories and working capital, keeping customers satisfied and in short: staying in business. Process mining methods make it possible to generate a large amount of transaction event data and case attributes that are useful for analysing lead times. However, finding root causes for long l...

The utility of multielement techniques for forensic analysis has been well documented in a recent article [1]. Typical analytical methods used for qualitative analysis include x-ray fluorescence (XRF), and emission spectroscopy (ES). Until the 1980's, neutron activation analysis (NAA) was the definitive method used for quantitative elemental analysis. However this technique has limited applicab...

Nowadays, the lead user method [von Hippel, Manag Sci 32(7):791– 805, 1986; Lüthje et al. (Res Pol 34(6):951–965, 2005)] and conjoint analysis [Green and Rao (J Market Res 8(3):355–363, 1971), Baier and Brusch (Conjointanalyse: Methoden Anwendungen Praxisbeispiele, Springer, Heidelberg, 2009)] are widely used methods for (new) product design. Both methods collect and analyze customers’ preferen...