BACKGROUND Low-density lipoprotein cholesterol (LDL-C) levels are the primary basis for treatment guidelines established for hyperlipidemic children and adolescents. Levels of LDL-C are commonly monitored by means of the Friedewald formula, an indirect calculation that requires an overnight fast. A new method has been developed for the direct measurement of LDL-C (DLDL-C) that does not require ...

Background & Objectives: Subclinical hypothyroidism is endocrine disorder where serum TSH levels are increased but FT4 within the assay's reference interval. Atherosclerosis has been found to be associated with level of Ox-LDL in SCH. The aim present study find out association and lipid profile SCH patients. Materials methods: 120 patients aged (18-70) years age sex-matched healthy controls...

BACKGROUND Epidemiological studies suggest that hypopituitary patients have an increased risk for cardiovascular mortality. The dyslipidaemia associated with this condition is often characterised by an increase in total cholesterol (TC) and low-density lipoprotein (LDL) cholesterol (LDL-C) and may contribute to these findings. The underlying mechanisms are not fully elucidated. MATERIALS AND ...

a dummy variable technique that allows simultaneous study of subgroup combinations from the placebo and treatment groups. Medwxs and Results. In the placebo group (n=2,045), the low density lipoprotein cholesterol (LDL-C)/high density lipoprotein cholesterol (HDL-C) ratio was the best single predictor ofcardiac events. This ratio in combination with the serum triglyceride level revealed a high-...

Low-density lipoprotein cholesterol (LDL-C) is frequently estimated using the empirical Friedewald equation. We compared the accuracy of the novel equation named as the 180-cell method (180-c), which estimates LDL-C using a stratification approach, to those of 9 previously suggested formulas, including the Friedewald equation.We compared the accuracy of 10 equations by calculating intraclass co...

AIM Since we previously reported that lower levels of HDL-C may be most useful for predicting coronary artery disease (CAD) as assessed by multi-detector row computed tomography (MDCT), we sought to confirm, among the levels of LDL-C, HDL-C, non-HDL-C (total cholesterol minus HDL-C) and the ratio of LDL-C to HDL-C (LDL-C/HDL-C), which is most closely related to the presence of CAD. METHODS AN...

This article is available online at http://www.jlr.org An increased low-density lipoprotein cholesterol (LDL-C) level is an established risk factor for cardiovascular disease. Statins (3-hydroxy-3-methylglutaryl CoA reductase inhibitors) effectively reduce LDL-C levels and the risk of cardiovascular events ( 1 ). Statins also diminish infl ammation as indicated by a reduction of C-reactive prot...