An anomalous zymogram of lactate dehydrogenase (LDH) in the serum from a patient with liver cirrhosis was reported. Agar-gel electrophoresis of serum showed an extra LDH band close to the anodic side of LDH5 and a wide band of LDH5. Gel filtration of patient's serum in Sephadex G-200 demonstrated an abnormal LDH fraction eluted between immunoglobulin G (IgG) and macroglobulin in addition to a n...

BDI agents have goals to achieve and a library of plans that can be used to achieve them, typically requiring adopting further goals. A Goal-Plan Tree (GPT) structure can be used to naturally represent the goals of BDI agents with the required plans and subgoals to achieve them. These can be used to significantly improve an agent’s deliberation and ability to make reasoned decisions on plan sel...

Gluten proteins from wheat, rye, barley and, in rare cases, oats, are responsible for triggering hypersensitivity reactions such as celiac disease, non-celiac gluten sensitivity and wheat allergy. Well-defined reference materials (RM) are essential for clinical studies, diagnostics, elucidation of disease mechanisms and food analyses to ensure the safety of gluten-free foods. Various RM are cur...

Upon immunization with LDH-III (subunit composition AABB) rabbits produce anti-A and anti-B antibodies in comparable amounts. These antibodies fit equally well to the hybrid enzyme and to LDH-V (AAAA) or LDH-I (BBBB) respectively, as tested by passive hemagglutination inhibition. No antibodies reacting with both LDH-I and LDH-V were detected. A minority of hybrid-specific antibodies was, howeve...

Both functional overload and hindlimb disuse induce significant energy-dependent remodeling of skeletal muscle. Lactate dehydrogenase (LDH), an important enzyme involved in anaerobic glycolysis, catalyzes the interconversion of lactate and pyruvate critical for meeting rapid high-energy demands. The purpose of this study was to determine rat soleus LDH-A and -B isoform expression, mRNA abundanc...

Open AI’s language model, GPT-3, has shown great potential for many NLP tasks, with applications in different domains. In this work we carry out a first study on GPT-3’s capability to communicate musical decisions through textual explanations when prompted representation of piece music. Enabling dialogue human-AI music partnerships is an important step towards more engaging and creative interac...

BACKGROUND Increased levels of lactic dehydrogenase (LDH) in the cerebrospinal fluid (CSF) have been reported in association with several intracranial pathologies. No studies have been performed on patients with Guillain-Barré syndrome (GBS). AIMS To study LDH isoenzymes in CSF of children with GBS. METHODS CSF samples collected from nine patients with GBS were analysed for total LDH isoenz...

Abstract This paper examines the ethical solutions raised in response to OpenAI’s language model Generative Pre-trained Transformer-3 (GPT-3) a year and half from its release. I argue that hype fear about GPT-3, even within Natural Language Processing (NLP) industry AI ethics, have often been underpinned by technologically deterministic perspectives. These perspectives emphasise autonomy of rat...

A protein with low LDH activity compared to recrystallized muscle LDH and one which appeared to be homogeneous by all available tests for protein homogeneity has been obtained in crystalline form from bovine and rabbit lenses. These lens LDH preparations appeared to be identical immunologically in the other mammalian species examined. The bovine lens LDH had half the molecular weight of LDH iso...

BACKGROUND Lactate formation is up-regulated in tumorous cells by lactate dehydrogenase (LDH). High serum LDH level is linked to many malignancies with poorer survival, but tumour LDH-5 has not been well investigated in non-small cell lung cancer (NSCLC). PATIENTS AND METHODS In 89 patients operated on for NSCLC stage I-III, the serum LDH level was assayed and immunohistochemistry for tumour ...