نتایج جستجو برای: lc msms

تعداد نتایج: 29613  

2017
Lindsay B Tulloch Stefanie K Menzies Andrew L Fraser Eoin R Gould Elizabeth F King Marija K Zacharova Gordon J Florence Terry K Smith

Current drugs to treat African sleeping sickness are inadequate and new therapies are urgently required. As part of a medicinal chemistry programme based upon the simplification of acetogenin-type ether scaffolds, we previously reported the promising trypanocidal activity of compound 1, a bis-tetrahydropyran 1,4-triazole (B-THP-T) inhibitor. This study aims to identify the protein target(s) of ...

2015
Josef Pannee

Alzheimer’s disease (AD) is the most common neurodegenerative disease among the elderly and accounts for 60-80% of all cases of dementia. Currently, the diagnosis of AD is based on cognitive tests and mental state exams, but the peptide amyloid-beta (Aβ) in cerebrospinal fluid (CSF) is increasingly used in clinical trials and settings. As for most protein and peptide biomarkers, quantification ...

2017
Jiwei He Alisa J. Stephens

In assessing the efficacy of a time-varying treatment Marginal Structural Models (MSMs) and Structural Nested Mean Models (SNMMs) are useful in dealing with confounding by variables affected by earlier treatments. MSMs model the joint effect of treatments on the marginal mean of the potential outcome, whereas SNMMs model the joint effect of treatments on the mean of the potential outcome condit...

2007

computational science iccs 2007 7th international lecture notes in computer science 4488 link.springer pursuitthe journey of an entrepreneur ebook | slangbasketball arousing the fury of the immune system a report from the 35 great childrens lessons that bring the bible to life the study skills handbook palgrave study skills ebook perspectives on philosophy of science in nursingan after the wrat...

Journal: :Environmental monitoring and assessment 2014
John E Elliott Sofi Hindmarch Courtney A Albert Jason Emery Pierre Mineau France Maisonneuve

Second-generation anticoagulant rodenticides are widely reported to contaminate and poison nontarget wildlife, primarily predatory birds and mammals. Exposure pathways, however, have not been well defined. Here, we examined potential movement of rodenticides from deployment of bait to exposure of small mammals and other biota. At two adjacent working farms, we placed baits containing either bro...

2014
Sajin Bae Cornelia M. Ulrich Marian L. Neuhouser Olga Malysheva Lynn B. Bailey Liren Xiao Elissa C. Brown Kara L. Cushing-Haugen Yingye Zheng Ting-Yuan David Cheng Joshua W. Miller Ralph Green Dorothy S. Lane Shirley A.A. Beresford Marie A. Caudill

Few studies have examined associations between plasma choline metabolites and risk of colorectal cancer. Therefore, we investigated associations between plasma biomarkers of choline metabolism [choline, betaine, dimethylglycine, and trimethylamine N-oxide (TMAO)] and colorectal cancer risk among postmenopausal women in a case–control study nested within the Women's Health Initiative Observation...

Journal: :Environmental pollution 2017
Min-Suk Bae James J Schauer Taehyoung Lee Ju-Hee Jeong Yoo-Keun Kim Chul-Un Ro Sang-Keun Song Zang-Ho Shon

This study investigated the relationship between water-soluble organic compounds of ambient particulate matter (PM) and cellular redox activity collected from May 28 to June 20 of 2016 at the west coastal site in the Republic of Korea during the KORea-US Air Quality (KORUS-AQ) campaign. Automatic four-hour integrated samples operated at a flow rate of 92 L per minute for the analysis of organic...

Journal: :journal of minimally invasive surgical sciences 0
diwakar sahu registrar, department of surgical gastroenterology and minimal access surgery, apollo hospitals, greams road, chennai, tamil nadu, india mittu john mathew registrar, department of surgical gastroenterology and minimal access surgery, apollo hospitals, greams road, chennai, tamil nadu, india prasanna kumar reddy registrar, department of surgical gastroenterology and minimal access surgery, apollo hospitals, greams road, chennai, tamil nadu, india; registrar, department of surgical gastroenterology and minimal access surgery, apollo hospitals, greams road, chennai, tamil nadu, india. tel: +91-4428290200, fax: +91-4428294429

results mean operative time was shortest in group a (57.1 minutes) and longest in group b [63.4 (p = 0.131)]. mean hospital stay was shortest in group a (2.1 days) and longest in group c (5.7 days) (p = 0.003). hospital expenses were minimal in group a (p = 0.001). male sex, serum bilirubin level, white blood cell (wbc) count, duration of ercp/es procedure, contracted gall bladder and large cal...

Elham Aliabadi, Fatemeh Karimi Tahereh Talaei-Khozani

Background: The glycoconjugate content of sperms indicates their physiological and fertility properties. Lectin reactivity is indicative of intact, capacitated, and acrosome-reacted sperms. In the epididymis, sperms experience maturation, glycoconjugate modification, and simultaneously, higher L-carnitine (LC) concentrations. The aim of this project was to evaluate the effects of LC and Pentoxi...

2004
Mohsen Bayati Neda Beheshti

Among scheduling algorithms used in input queued switches, it is known that the Maximum Size Matching (MSM) algorithm maximizes the instantaneous throughput. Although there have been results on the stability of some specific types of MSMs for scheduling traffic [5], the question of how it performs under uniform traffic remains open. Simulations suggest the stability of MSM algorithms under unif...

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