نتایج جستجو برای: latency associated transcript lat

تعداد نتایج: 1587075  

Journal: :Journal of virology 1991
A K Cheung

A collection of overlapping cDNA clones encoding the latency transcript of pseudorabies virus and the DNA nucleotide sequence of the latency gene has been obtained. The transcript is spliced with 4.6 kb of intervening sequences. This mRNA, designated the large latency transcript, is 8.5 kb. It is polyadenylated and contains a large open reading frame capable of coding for a 200-kDa polypeptide....

Journal: :Journal of virology 1997
J M Hill H H Garza Y H Su R Meegalla L A Hanna J M Loutsch H W Thompson E D Varnell D C Bloom T M Block

In this study we used a herpes simplex virus type 1 (HSV-1) deletion mutant to identify a segment of the genome necessary for epinephrine-induced reactivation in the rabbit eye model of herpetic recurrent disease. In HSV-1 latently infected neural tissue, the only abundant viral products are the latency-associated transcripts (LATs). At least one promoter of LAT has been identified, and mutatio...

2016
Zhaohui Sun Huilan Yang Linhai Li Min Wei Shaoshan Xu Jiang Xian Yuli Feng Wurong Lin

Objective: To establish cell model of herpes simplex virus type 2 latent infection and reactivation in SHSY5Y cells. Methods: Effects of ACV on SH-SY5Y cells were observed after cells were treated with ACV concentrations of 20, 40, 60, 80, 100, 120, or 140 μmol/L, and also cells morphology was observed under phase contrast microscope after HSV-2 was inoculated into SH-SY5Y cells using MOI of 0....

2014
Mihajlo Jakovljevic Mirjana Jovanovic Nemanja Rancic Benjamin Vyssoki Natasa Djordjevic

Lesch Alcoholism Typology (LAT) is one of the most widely used clinical typologies of alcohol addiction. Study tested whether introduction of LAT software in clinical practice leaded to improved outcomes and reduced costs. Retrospective matched-pairs case-control cost comparison study was conducted at the Regional Addiction Center of the University Clinic in Serbia involving 250 patients during...

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