PURPOSE To make assessments of the rates of cases of larynx cancer in Lithuania in the years 1978-2001 as well as possible trends of changes in the future. MATERIAL AND METHODS The data contained in the Lithuanian Cancer Register for the period 1978-2001 about new cases as well as the data compiled by the Lithuanian Department of Statistics on the average number of population of Lithuania wit...

In medical history of different nations, there are numerous documents concerning cancer. The present study is an investigation in ancient books to determine the part that medicine of Iran has played in the recognition of cancer. In all 31 Iranian medical and 5 Islamic medicine books mostly from 8 to 18 cent. A.D. have been examined. The findings showed that cancer in ancient medical books of Ir...

introduction: cigarette smoking and alcohol consumption have a well-known effect on the development of upper aerodigestive tract carcinomas, but such a role for opium is questionable. this study was designed to assess the correlation between opium inhalation and cancer of the larynx and upper esophagus. materials and methods: fifty eight patients with laryngeal cancer, ninety eight patients wit...

Acrylamide exposure has been related to an increased incidence of oral and thyroid tumors in animal studies. In 1986, 120,852 persons (aged 55-69 years) were included in the Netherlands Cohort Study. Dietary acrylamide intake was assessed with a food frequency questionnaire and was based on chemical analysis of all relevant Dutch foods. Hazard ratios were adjusted for smoking and other confound...

Aziridine-containing compounds have been of interest as anticancer agents since late 1970s. The design, synthesis and study of triaziquone (TZQ) analogues with the aim of obtaining compounds with enhanced efficacy and reduced toxicity are an ongoing research effort in our group. A series of bis-type TZQ derivatives has been prepared and their cytotoxic activities were investigated. The cytotoxi...

CANCER of the lung is held to be increasing in incidence, probably on a worldwide basis. This paper presents data on cancers of the lung, trachea and larynx based on the post-mortem protocols of the University and Government Departments of Pathology, Singapore, and on the reports of the Registrar-General, Siingapore, in the hope that the information adduced will prove useful as a baseline for s...

BACKGROUND Occupational exposure to silica dust occurs in many workplaces and is well known to cause silicosis. However, the link between silica exposure, silicosis and other diseases is still disputed. AIMS To evaluate cause-specific mortality in a cohort of Italian silicotics. METHODS The cohort included 2034 male compensated for silicosis between 1943 and 1986, alive on 1 January 1987 an...

Abstract Background:Cancer of the larynx is a common cancer of the head and neck. This cancer has an established correlation with smoking tobacco and alcohol as causative agents. This study has been conducted in a tertiary hospital in Northeastern India. Minimal data about laryngeal cancer from this area was published in the literature. Methods: This prospective study was conducted for a period...

This is a review of the epidemiologic literature on alcohol and risks of various cancers. Alcohol has consistently been related to risks of squamous cell carcinomas of the mouth, oral pharynx, larynx, and esophagus in multiple studies of varying design. The joint effects of alcohol and smoking are greater than additive, and are probably multiplicative, suggesting biological synergism. All major...

Accessible online at: www.karger.com/journals/orl Cancer of the larynx constitutes 1–2% of all malignancies diagnosed annually worldwide and represents the most common head and neck malignancy in the United States, as recently reported by the National Cancer Data Base [1]. Survival in patients with laryngeal cancer is dependent on the stage and site of tumour and its phenotype. It is obviously ...