Laryngeal squamous cell carcinomas (LSCC) are the most frequently seen cancers among head and neck squamous cell carcinomas (HNSCC), and they constitute 1-2% of all malignancies worldwide (Sadri et al., 2006). Laryngeal carcinogenesis is a multifactorial process that has not been fully elucidated. LSCC develops as a result of structural and cytological alterations in the laryngeal squamous epit...

Background:The incidence rate of head and neck cancer in the world is about 560,000 new cases a year. Larynx cancer is the most common malignancy in head and neck in Iran. The most common head and neck carcinoma is the malignancy of squamous epithelial cells. This study was conducted to determine the survival rate of patients undergoing nonsurgical treatment methods for larynge...

Objective This study aimed to evaluate the recurrence and survival of patients treated with frontolateral laryngectomy for T1 and T2 glottic laryngeal carcinoma. Methods Patients who underwent frontolateral laryngectomy for glottic laryngeal carcinoma at a tertiary hospital between March 2009 and June 2014 were included. Patient demographics, tumor stage, treatment and histopathological exami...

Preservation of the larynx is the most critical factor influencing quality of life in the treatment of head and neck cancer. This clinical study focuses on laryngeal function-preserving chemoradiotherapy for locally advanced hypopharyngeal and laryngeal cancer. Thirty-two resectable cases with histologically proven squamous cell carcinoma undergoing function-preserving therapy were examined. In...

BACKGROUND The human trophoblastic cell surface antigen 2 (TROP2) gene is associated with the development of malignancies, but its expression in laryngeal squamous cell carcinoma (SCC) and its relationship with clinical characteristics of the disease remain undetermined. METHODS Expression of TROP2 protein was detected by immunohistochemistry with a self-made anti-TROP2 antibody in laryngeal ...

introduction: a rare case of basaloid squamous cell carcinoma (bscc) of the larynx, which has not been previously reported, is described. case report: a 60-year-old man was presented to the otolaryngology department with progressive dyspnoea and dysphagia to solids for over a period of 1 week. direct laryngoscopy revealed a tumour at the laryngeal aspect of the epiglottis, which prolapsed into ...