Large cardiac spheroids (i.e., > 500 µm diameter) that self-induce an ischemic core were generated by co-culture of cardiomyocytes derived from induced pluripotent cells (hiPSC-CMs) and primary fibroblast (hCF). Without modification culture conditions, spheroids’ large size allowed the recreation a dead core, fibrotic remodelling tissue stiffening.

Primary cardiac sarcomas are rare. In such tumors, surgical resection is sometimes considered necessary to correct obstruction of flow caused by the tumor and to accomplish complete resection. The anatomic difficulties associated with large, primary, intracavitary left-sided sarcomas have led us to use cardiac explantation, ex vivo tumor resection, and cardiac autotransplantation to meet the an...

TOPIC: Disorders of the Mediastinum TYPE: Medical Student/Resident Case Reports INTRODUCTION: Lymphoma is fourth most common malignancies in pregnancy, and a high portion primary mediastinal (thymic) large B-cell lymphoma (PMBCL). It presents many challenges to diagnose during pregnancy while avoiding fetal harm. CASE PRESENTATION: 41-year-old G2P1 female without significant past medical histor...

To eanpare the modMod precordiat leads MCI., and AlCL, with the conventioosl prfxordial leads V, and V, and assess the diignastic necuracy of selected leads for continuous bedside electrocardiographic (ECGI monitoring. 121 wide QRS complex tachycardiis were recorded From 92 palienls during cardiac electrophyG&gic rNdy. As awzNined from intracardiac recordings, 86 Nchycardias were venlricular an...