BACKGROUND During competition, high-performance swimmers are subject to repeated physical demands that affect their final performance. Measurement of lactate concentration in blood seeks to indirectly gauge physiologic responses to the increase in physical exercise. Swimmers face multiple maximal-exertion events during competition. Strenuous physical exercise leads to fatigue and, thus, a decre...

Aquatic and terrestrial crustaceans are dependent on both aerobic and anaerobic metabolism for energy production during exercise. Anaerobic energy production is marked by an accumulation of lactate in both muscle tissue and haemolymph, but the metabolic fate of lactate is not clear. Lactate recycling via gluconeogenesis and the potential role of carbonic anhydrase (CA) in supplying bicarbonate ...

Introduction: During the course of systemic inflammation, most of the immune cell types get activated to a certain degree as part of, or contributing to, the cascade of physiopathological events. Whether for some cells, classically phagocytes of the innate immune system, it is clear that direct sensing of pathogen-associated molecular patterns leads to activation initiating systemic inflammatio...

the nasal cavity possesses many advantages as a site for drug delivery, such as, ease of administration, applicability for long term treatments and a large surface area for absorption. one important limiting factor for nasal drug delivery is the limited time available for absorption within the nasal cavity due to mucociliary clearance. several drug delivery systems including different kinds of ...

www.chestpubs.org 5 . Jones AE , Shapiro NI , Trzeciak S , Arnold RC , Claremont HA , Kline JA ; Emergency Medicine Shock Research Network (EMShockNet) Investigators . Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial . JAMA . 2010 ; 303 ( 8 ): 739 746 . 6 . Rivers EP . Point: adherence to early goal-directed therapy: does it rea...

The goal of this study was to define the individual model characteristics lactic acid removal after 200m breaststroke competitive load in a female swimmer relation different pool lengths (25m vs. 50m). second methodological and referred presentation newly applied metrological procedures for Individual Lactate Recovery Profile modeling. Six races from season 2021/22 were selected, which athlete ...

Background: Sepsis is the first leading cause of death in Myanmar and complications are also difficult to solve. This study aimed detect effect thiamine on lactate clearance mortality patients with sepsis. Method: A randomized controlled trial done No.(1) Defence Services General Hospital, Yangon from October 2020 June 2022. All > 18 years old admitted suspected or documented infection qSOFA...