Background. This study described various molecular and epidemiological characters determining antibiotic resistance patterns in Pseudomonas aeruginosa isolates. Methods. A total of 34 carbapenem-resistant P. aeruginosa clinical isolates were isolated from samples collected at a tertiary hospital in Riyadh, Saudi Arabia, from January to December 2011. Susceptibility testing, serotyping, molecula...

INTRODUCTION Extended-spectrum β-lactamase (ESBL)-producing strains of Enterobacteriaceae are considered to be emerging pathogens. They are a major problem in hospitalized as well as community-based patients. Major outbreaks involving ESBL strains have been reported from all over the world. Recurrent urinary tract infection (UTI) is one of the risk factors for infection with ESBL-producing E. c...

BACKGROUND The emergence of carbapenem-resistant Klebsiella pneumoniae poses a serious problem to antibiotic management. We investigated the β-lactamases in a group of carbapenem-resistant K. pneumoniae clinical isolates from Turkey. METHODS Thirty-seven strains of K. pneumoniae isolated from various clinical specimens were analyzed by antimicrobial susceptibility testing, PCR for the detecti...

NDM-positive Salmonella sp. strain identified in the United States. Antimicrob Agents Chemother. 2011;55:5957–8. http://dx.doi.org/10.1128/AAC.05719-11 5. Centers for Disease Control and Prevention. Carbapenem-resistant Enterobacteriaceae containing New Delhi metallo-βlactamase in two patientsRhode Island, March 2012. MMWR Morb Mortal Wkly Rep. 2012;61:446–8. 6. Centers for Disease Control and...

We aimed to investigate carbapenem resistance, resistance mechanisms, risk factors and epidemiological features of Escherichia coli and Klebsiella pneumoniae strains isolated from related infections in intensive care unit (ICU) patients. Carbapenemase activity was determined by MHT, MBL Etest and enzyme extraction methods. Presence of extended-spectrum b-lactamase (ESBL) and carbapenemaseencodi...

Severe diabetic foot ulcers (DFUs) patients visiting Sir Sunderlal Hospital, Banaras Hindu University, Varanasi, were selected for this study. Bacteria were isolated from swab and deep tissue of 42 patients, for examining their prevalence and antibiotic sensitivity. DFUs of majority of the patients were found infected with Enterococcus spp. (47.61%), Escherichia coli (35.71%), Staphylococcus sp...

introduction: extended spectrum beta-lactamase (esbl) producing escherichia coli generate a major problem for clinical therapeutics and epidemiological study. the incidence of esbl producing strains among clinical isolates has been steadily increasing during the past few years, and remains an important cause of failure of therapy with cephalosporins. the aim of this study was to determine the a...

Due to an increase in serious infections and a lack of efficient therapies, Klebsiella pneumoniae has recently gained more recognition. The production carbapenemases is one the most common strategies by which K. acquire resistance carbapenems considered last resort antibiotics. Previously collected isolates from different clinical settings on basis their genetic profile, mainly absence presence...

Escherichia coli (E. coli) strains placed in predominant nosocomial bacteria intensive care units (ICUs), resulting severe drug-resistant infections. Non-susceptibility to β-lactams and last-line drugs such as Fosfomycin Colistin cause limited availability of infections eradication. The objective this study included the determination genes encoding extended-spectrum β-lactamase (ESBL), Carbapen...