The measurement of concentrations of drugs and endogenous substances is widely used in basic and clinical pharmacology research and service tasks. Using data science-derived visualizations of laboratory data, it is demonstrated on a real-life example that basic statistical exploration of laboratory assay results or advised standard visual methods of data inspection may fall short in detecting s...

Allergic diseases, such as atopic eczema, food allergy, rhinitis and wheezing disorders are among the most fre­ quent complaints, especially in childhood. The current evidence also attests that type I allergic reactions are becoming more and more widespread, affecting up to 20% of the population. The World Health Organization (WHO) recently estimated that approximately 300 million people suffer...

In healthcare domain, reporting of laboratory results by biomedical scientists to caregivers is a common practice. Many healthcare centres follow different kind of guidelines for reporting laboratory results for the purpose of improving the process. In this paper, we first analyze current procedure for reporting Critical Laboratory Results (CLRs) followed by North Estonia Medical Centre (NEMC) ...

The results of investigations in laboratory medicine are used for many purposes. Most are performed for monitoring individuals in acute situations and following the improvement or deterioration of chronic disease. In diagnosis, case-finding, and screening, conventional population-based reference intervals are relevant, and they are partitioned if necessary according to age, sex, or other import...

Introduction The rising cost of clinical research is driving the current trend of outsourcing to developing countries. Many developing countries, such as Ghana, conduct research but face many challenges in ensuring that the trial conduct and results conform to international standards. Such challenges include staff recruitment and retention and the reliability of laboratory results. Ethical aspe...

We examined the value of laboratory markers of excessive alcohol (ethanol) intake as predictors of mortality, morbidity, and health-care utilization in a cohort of 330 patients attending an acute ambulatory care service. Among men, all four markers examined--gamma-glutamyltransferase (GGT) and aspartate aminotransferase (AST) activities, high-density lipoprotein cholesterol (HDL-C), and mean co...

A new computerized format for presenting microbiology laboratory results has been designed and evaluated. This new system uses an index format providing a concise summary of the status of each test ordered and the results for each test organized by the source of the specimen on the first page of the report. This is followed by complete, detailed microbiology results sorted in reverse chronologi...

We developed a three-dimensional gaseous tracking device and performed a directionsensitive dark matter search in a surface laboratory. By using 150 Torr carbontetrafluoride (CF4) gas, we obtained a sky map drawn with the recoil directions of the carbon and fluorine nuclei, and set the first limit on the spin-dependent WIMP (Weakly Interacting Massive Particles)-proton cross section by a direct...

Medical literature contains expressions of laboratory examination results, which are invaluable knowledge sources for building a disease knowledge base that covers even rare diseases. In this study, we analyzed such expressions of disease descriptions in open databases with manually built dictionaries and obtained the following results. First, we identified two major types of expressions for la...

During the last 25 years, clinical autoantibody determinations have changed dramatically. Old and slow techniques with high diagnostic specificity have been replaced with automated and faster techniques that most often have a higher diagnostic sensitivity at the expense of a lower diagnostic specificity. Newer techniques are mostly quantitative, allowing for follow-up of autoantibody levels. Wh...