objective: angiogenesis a process that results in neo-vascularization is an essential stage in growth of solid tumors and the formation of metastases. vascular endothelial growth factor (vegf) and its receptors, vegfr1 (flt-1) and vegfr2 (kdr/flk-1), are the major regulators for tumor angiogenesis. recent studies showed that second domain of vegfr-1is a key factor for vegf/vegfr-1 interaction. ...

Tyrosinase enzyme is an that plays important role in melanin synthesis. This will oxidize the amino acid L-tyrosine into L- 3,4 dihydroxyphenylalanine (L-DOPA) and convert L-DOPA DOPAquinone. protein from Bacillus megaterium complex with inhibitor kojic target interact ligand (Drug Candidate), Temulawak (Curcuma xanthorrhiza) one of medicinal plants Zingiberaceae family which widely grown used ...

to evaluate the role of wild promoter of l-phenylalanine dehydrogenase (phedh) gene, referred to as pdh, from bacillus sphaericus in expression, cloning of pdh gene in bacillus subtilis was performed. the whole pdh gene was cloned in phy300plk shuttle vector and amplified, construct (phydh) then transformed in b. subtilis isw1214 and e. coli jm109. the pdh endogenous promoter presented no effec...

The pathogenesis of neurodegenerative diseases is believed to involve abnormal aggregation of proteins, but the mechanisms initiating protein aggregation are unclear. Here we report a novel phenomenon that could be instrumental in triggering protein aggregation in neurodegenerative diseases. We show that the 3' untranslated region (3'UTR) of a light neurofilament (NF-L) transcript enhances the ...

Objetive. To evaluate the effect of two types fertilizers on phytomass and protein content hydroponic green forage (FVH) corn (Zea mays L.), rice (Oryza sativa L.) soybean (Glycine max L.). Design/methodology/approach. A 32x32 bifactorial design was implemented. The seeds were disinfected with 1 % chlorine by immersion for 15 min. system nebulization irrigation used frequency every 4 hours 5 cm...

Experiments were conducted at three sites across southern New South Wales, Australia, over years (2008 to 2010), evaluate the agronomic and quality parameters of two wheat (Triticum aestivum L.), barley (Hordeum vulgare oat (Avena sativa L.) one triticale (× Triticosecale) variety, grown as monocultures or in combination with purple vetch (Vicia benghalensis L.). Harvests occurred when individu...

tuberose (polianthes tuberosa l.) is an important commercial cut flower that has a short vase life. an experiment was carried out by using five different levels of humic acid (ha) (0, 25, 50, 75, and 100 mg l-1) and seven different levels of silver nano-particles (snp) (0, 0.5, 1, 2, 3, 4 and 5 mg l-1) mixed with 1.5% sucrose on cut tuberosa cv. single flower. the loss of fresh weight on third ...