نتایج جستجو برای: kpc gene
تعداد نتایج: 1147958 فیلتر نتایج به سال:
We investigated a novel Japanese isolate of sequence type 11 (ST11), the Klebsiella pneumoniae carbapenemase-2 (KPC-2)-producing K. pneumoniae strain Kp3018, which was previously obtained from a patient treated at a Brazilian hospital. This strain was resistant to various antibiotic classes, including carbapenems, and harbored the gene blaKPC-2, which was present on the transferable plasmid of ...
OBJECTIVES The origin of KPC is unknown. The aim of this study was to detect progenitors of KPC in silico and to functionally verify their β-lactam hydrolysis activity. METHODS The sequence of KPC-2 was used to mine the NCBI protein sequence database. The best non-KPC hits were analysed by amino acid (aa) alignment and phylogenetic tree construction. Genes encoding KPC-2 homologues were expre...
OBJECTIVES To develop a single multiplex real-time PCR assay to detect six different genetic types of carbapenemases already identified in Enterobacteriaceae (KPC, GES, NDM, IMP, VIM and OXA-48). METHODS A total of 58 bacterial isolates were tested. Thirty were previously characterized as resistant to carbapenems and documented by PCR and sequencing analysis to carry the following genes: bla(...
The isolation of OXA-48-producing Enterobacteriaceae has increased dramatically in Mediterranean countries in the past 10 years, and has recently emerged in Asia. Between January 2012 and May 2014, a total of 760 carbapenem non-susceptible Klebsiella pneumoniae (CnSKP) isolates were collected during a Taiwan national surveillance. Carbapenemases were detected in 210 CnSKP isolates (27.6%), incl...
چکیده سابقه و هدف: هدف از این مطالعه، تعیین شیوع ژن های متالوبتالاکتاماز (mbl) و کلبسیلا پنومونیه کارباپنماز (kpc) در بین ایزوله های سودوموناس آئروژینوزای جدا شده از بیماران مبتلا به سوختگی و سیستیک فیبروزیس بود. مواد و روش ها: این مطالعه توصیفی بر روی 70 و 30 ایزوله سودوموناس آئروژینوزای جدا شده از زخم بیماران مبتلا به سوختگی بیمارستان مطهری تهران و خلط بیماران مبتلا به سیستیک فیبروزیس بیمارس...
We read with great interest the article by Andrade et al. (1) describing the predominance of sequence type 258 (ST258) among KPC-2-producing Klebsiella pneumoniae isolates in Brazilian hospitals. Recently, we conducted a similar study that evaluated the genetic relationship among KPC-2-producing K. pneumoniae isolates from Brazilian hospitals. A total of 34 KPC-2-producing K. pneumoniae isolate...
We describe the interspecies transmission of the plasmid-mediated blaKPC-3 gene, which confers carbapenem resistance, between clinically relevant gram-negative bacteria in a single patient. A KPC-3 producing Enterobacter aerogenes was isolated from a hospitalized patient previously colonized and then infected by a Klebsiella pneumoniae ST101 carrying the blaKPC-3 gene. The strains showed identi...
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