Since the food matrix determines β-carotene availability for intestinal absorption, food matrix effects on the bioaccessibility of β-carotene from two diets were investigated in vitro and compared with in vivo data. The "mixed diet" consisted of β-carotene-rich vegetables, and the "oil diet" contained β-carotene-low vegetables with supplemental β-carotene. The application of extrinsically label...

Data for the spectral light absorption of pure water from 250 to 550 nm have been obtained using an integrating cavity made from a newly developed diffuse reflector with a very high UV reflectivity. The data provide the first scattering-independent measurements of absorption coefficients in the spectral gap between well-established literature values for the absorption coefficients in the visibl...

Solubility of drug plays critical role in achieving the optimum therapeutic levels of the drug in blood and thus bioavailability. There are many drugs of various therapeutic categories fall in BCS class II and IV as they lack solubility. For all these drugs dissolution is the big hurdle for the absorption process. Present review’s focus is mainly on novel techniques of improving the solubility ...

Introduction Conclusions References

A novel set of molecular descriptors suitable for use in quantitative structure-activity relationships and related methods is described. These descriptors are a smooth and interpretable representation of atomic physicochemical property values and intramolecular atom pair distances. Distance atomic physicochemical parameter energy relationships (DAPPER), a novel structure-activity relationship (...

The detectivity D* limits of YBa(2)Cu(3)O(7-x) bolometers on 0.05-cm-thick crystalline substrates are investigated, and a method to increase D* to greater than 10(9) (cm Hz(1/2))/W at a 20-microm wavelength is proposed. Because the response increases proportionally with the bias current I(b), whereas the noise near T(c) (the transition or critical temperature) of our MgO and SrTiO(3) substrate ...

Recently, analytical solutions of a nonlinear Fokker-Planck equation describing anomalous diffusion with an external linear force were found using a nonextensive thermostatistical Ansatz. We have extended these solutions to the case when an homogeneous absorption process is also present. Some peculiar aspects of the interrelation between the deterministic force, the nonlinear diffusion, and the...

Introduction Malnutrition and coexisting micronutrient deficiencies are common in the developing world. A high prevalence of anemia is found in Cambodia with children and women being the most affected. Anemia is defined as lack of red blood cells, resulting in impaired blood function and poor oxygen transport. Iron deficiency (ID) is often an underlying factor of anemia. Diet modifications to i...

The diagnosis of congenital syphilis is difficult since it depends mainly on the results of serological tests. The results of five serological tests (three specific and two non-specific) in nine neonates with congenital syphilis are compared with those obtained in three with passively acquired antibodies. It appeared that the serological diagnosis of congenital syphilis must be based on the fin...