how to cite this article: tonekaboni sh, ebrahimi a, bakhshandeh bali mk, houshmand m, moghaddasi m, taghdiri mm, nasehi mm. sodium channel gene mutations in children with gefs + and dravet syndrome: a cross sectional study. iran j child neurol. 2013 winter; 7 (1):25-29.   objective dravet syndrome or severe myoclonic epilepsy of infancy (smei) is a baleful epileptic encephalopathy that begins ...

hyper ige syndrome (hies) is a rare primary immunodeficiency disease. most of hies cases are sporadic. hies type ad is caused by mutation in signal transducer and activator of transcription-3 (stat-3). a number of mosaicism hies has been reported that is associated with intermediate phenotype. autosomal recessive hies (ar-hies) is due to mutation in dock-8 or cytokine sis 8 and tyk2 or tyrosine...

background: phytoestrogens are a group of plants derived compounds with weekly estrogen effect that appear to have protective effects on metabolic and hormonal abnormalities of women with polycystic ovary syndrome (pcos). so the aim of this study was to investigate the effect of soy phytoestrogens on reproductive hormones and lipid profiles in pcos women. methods: in this quasi-randomized trial...

background: the correlation of metabolic syndrome and migraine headache was evaluated in some previous studies. however there is no study that compared the prevalence of metabolic syndrome in the patients with and without migraine. control of coincidental factors such as metabolic syndrome reduces therapeutic resistance in migrainous patients. the aim of this study was to compare prevalence of ...

conclusions in our study, portal venous thrombosis was detected in the patient who died during the acute period only. a study including large numbers of budd-chiari-syndrome patients with behcet’s disease and portal venous thrombosis would be helpful to determine the prognostic significance of portal venous thrombosis in budd-chiari-syndrome patients with behcet’s disease. in addition, patients...

modeling of relationship between ventilation rate of buildings and sick building syndrome symptoms hosseinpoor s , gholamiborujeni f *, mohammadian y received: 22 aug, 2013 accepted: 23 oct , 2013 abstract background & aims: indoor air pollution with microbilal, chemical and physical pollutants lead to sick building syndrome (sbs). suitable ventilation of buildings, is one of the best methods t...

turner syndrome is a sex-chromosome disorder occurring in one out of 2500 female births and characterized by growth retardation, gonadal dysgenesis and cardiovascular anomalies. the 45, xo karyotype is the most frequent type of this disease. herein, we report on a 6-year-old girl with turner syndrome and 45, xo karyotype presenting with short stature. she had dextrocardia and hiatal hernia. to ...

background: nephrotic syndrome and type 1 diabetes mellitus are two common chronic conditions in children. co-existence of these conditions is an extremely rare finding. case presentation: this report presents a 6-year-old boy who was diagnosed with nephrotic syndrome five years ago and type 1 diabetes mellitus in infancy. renal biopsy showed membranous glomerulonephritis, which is a rare histo...

hemophagocytic syndrome is a non-malignant process that is characterized clinically by fever, hepatomegaly, splenomegaly, pancytopenia in peripheral blood, and reactive histiocytes in the bone marrow. bacterial infectious diseases like typhoid fever and brucellosis and viral infections including cmv, herpes viruses, and epstein-barr virus are diagnosed as the cause of this syndrome. in this pap...