Spectrophotometric method is often recommended in dissolution testing of not only tablets or capsules but also suppositories. Dissolution rate of diclofenac sodium was studied using a pharmacopoeial flow-through apparatus and pH 7.3 buffer. For two lipophilic suppository bases (Witepsol W-32 and H-19) dissolution rate was overestimated with the spectrophotometric zero-order method in comparison...

In this note, we prove the generic Kobayashi volume measure hyperbolicity of singular directed varieties (X,V ), as soon as the canonical sheaf KV of V is big in the sense of Demailly.