نتایج جستجو برای: kinetic inhibitor
تعداد نتایج: 295228 فیلتر نتایج به سال:
A computer program with the code name DYNAFIT was developed for fitting either the initial velocities or the time course of enzyme reactions to an arbitrary molecular mechanism represented symbolically by a set of chemical equations. Seven numerical tests and five graphical tests are applied to judge the goodness of fit. Experimental data on the inhibition of the dissociative dimeric proteinase...
Protein arginine methyltransferase 1 (PRMT1) is a key posttranslational modification enzyme that catalyzes the methylation of specific arginine residues in histone and nonhistone protein substrates, regulating diverse cellular processes such as transcriptional initiation, RNA splicing, DNA repair, and signal transduction. Recently the essential roles of PRMT1 in cancer and cardiovascular compli...
Tyrosinases are responsible for melanin formation in all life domains. Tyrosinase inhibitors are used for the prevention of severe skin diseases, in skin-whitening creams and to avoid fruit browning, however continued use of many such inhibitors is considered unsafe. In this study we provide conclusive evidence of the inhibition mechanism of two well studied tyrosinase inhibitors, KA (kojic aci...
The partial purification and characterization of a factor from skeletal muscle which inhibits the activity of adenosine 3’,5’-monophosphate-dependent protein kinases from skeletal muscle, heart, liver, adipose tissue, and brain is described. The inhibitor is stable to heating at 96” and to precipitation with 5%, w/v, of trichloracetic acid, but is assumed to be a protein since it is inactivated...
The inhibition effect of N-benzyl-N′-phenyl thiourea (BPTU) on the corrosion of mild steel in 0.01 and 0.05 N HCl medium has been investigated by potentiostatic polarization technique. Results obtained reveal that BPTU is an efficient anodic inhibitor with greater than 94% of efficiency in the range of temperature studied. The adsorption of inhibitor on the mild steel surface obeys the Temkins’...
1. Kinetic measurements of the forward reaction catalysed by ATP-galactose phosphotransferase were carried out with a purified preparation from pig liver. 2. The rate of reaction at pH7.8 is dependent on the concentration of MgATP(2-) rather than total ATP or magnesium chloride concentrations. 3. The effect of changes in pH on K(m) (galactose), K(m) (MgATP(2-)) and V(max.) was studied. 4. Of se...
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