See the article "Electronic alert outpatient protocol improves quality of care for risk postcontrast acute kidney injury following computed tomography" in Volume 42 on page 606.

Organ cross talk exists in many diseases of the human and animal models of human diseases. A recent study demonstrated that inflammatory mediators can cause acute kidney injury and neutrophil infiltration in a mouse model of dextran sodium sulfate (DSS)-colitis. However, the chemokines and their receptors that may mediate distant organ effects in colitis are unknown. We hypothesized that kerati...

renal ischemia-reperfusion (ir) injury is a common problem in kidney transplantation. there is increasing evidence about the role of the reactive oxygen species (ros) in these injuries and endogenous antioxidants seem to have an important role in decreasing the renal tissue injury. the aim of this study was to investigate the effects of kidney ir on renal antioxidant enzymes activity such as ca...

INTRODUCTION Whether discernible advantages in terms of sensitivity and specificity exist with Acute Kidney Injury Network (AKIN) criteria versus Risk, Injury, Failure, Loss of Kidney Function, End-stage Kidney Disease (RIFLE) criteria is currently unknown. We evaluated the incidence of acute kidney injury and compared the ability of the maximum RIFLE and of the maximum AKIN within intensive ca...

BACKGROUND Acute kidney injury is a common complication of liver transplantation. In this single-centre retrospective observational study, we investigated the impact of acute kidney disease on liver recipient survival. METHODS The study population consisted of patients who underwent a liver engraftment between January 2002 and November 2006, at a single transplantation centre in São Paulo, Br...

INTRODUCTION Dyschloremia is common in critically ill patients, although its impact has not been well studied. We investigated the epidemiology of dyschloremia and its associations with the incidence of acute kidney injury and other intensive care unit outcomes. MATERIAL AND METHODS This is a single-center, retrospective cohort study at Mayo Clinic Hospital-Rochester. All adult patients admit...

The aging kidney is a marked by a number of structural and functional changes, including an increased susceptibility to acute kidney injury (AKI). Previous studies from our laboratory have shown that aging male Fischer 344 rats (24 month) are more susceptible to apoptosis-mediated injury than young counterparts. In the current studies, we examined the initial injury and early recovery phases of...

OBJECTIVES To apply the RIFLE criteria "risk," "injury," and "failure" for severity of acute kidney injury to patients admitted to the intensive care unit and to evaluate the significance of other prognostic factors. DESIGN Retrospective analysis of the Riyadh Intensive Care Program database. SETTING Riyadh Intensive Care Unit Program database of 41,972 patients admitted to 22 intensive car...

*Corresponding author: Prof. Hamid Nasri, Department of Nephrology, Division of Nephropathology, Isfahan University of Medical Sciences, Isfahan, Iran. Tel: +98 311 220 8081, Fax: +98 311 223 5043, E-mail: [email protected] Last year, the International Society of Nephrology (ISN) and the International Federation of Kidney Foundations (IFKF), focused the World Kidney Day (WKD) of 2013 on acut...

Acute kidney injury is an independent risk factor for patient mortality, even with small decrements in kidney function. In addition, it increases length of stay in the hospital and increases cost of treatment. Renal injury is often multifactorial, with drugs being only one of the factors in its pathogenesis. Hence, it is often difficult to estimate involvement of drugs as a cause of acute kidne...