it is assumed that about 10% of individuals infected with mycobacterium tuberculosis develop tuberculosis. the rate of tuberculosis in solid organ transplant recipients has been estimated to be 50-fold higher than in the general population. candidates for solid organ transplantation are routinely screened for latent tuberculosis infection (ltbi). in this study we aimed to compare tuberculin ski...

background nephrotoxicity is characterized and scored by many parameters such as vacuolization, dilatation, hyaline cast, debris or degeneration in injured renal tissue. in this short report, we attempt to find, the most correlated parameters with kidney tissue pathology damage score (pds) in cisplatin-induced nephrotoxicity. method a total of 207 normal and toxic rats’ kidney tissue (induced b...

Chlorambucil is an anticancer drug with alkylating and immunosuppressive properties. The present findings show that the combination treatment of tumor-bearing mice with ascorbic acid plus chlorambucil has much better therapeutic efficacy against murine ascites Daltons’ lymphoma in comparison to chlorambucil alone and this may involve a decrease in GSH in Dalton's lymphoma tumor cells. Chlorambu...

nitric oxide (no) is implicated as an important mediator of, or intermediary in, inflammation, immunity and neurotransmission. in the kidney, no is involved in haemodynamic regulation, control of vascular tone and tubular function. formation of oxygen-derived free radicals (ofr) have been documented in renal ischaemia- reperfusion before. in this study , we investigated the significance of no f...

Chlorambucil is an anticancer drug with alkylating and immunosuppressive properties. The present findings show that the combination treatment of tumor-bearing mice with ascorbic acid plus chlorambucil has much better therapeutic efficacy against murine ascites Daltons’ lymphoma in comparison to chlorambucil alone and this may involve a decrease in GSH in Dalton's lymphoma tumor cells. Chlorambu...

background: diabetic nephropathy (dn) is one of the most important complications of diabetes mellitus. now-a-days, cystatin c (cysc) is introduced as a new marker for diagnosis of renal damages; however, use of this marker in clinical laboratories is still controversial. the present study was aimed to evaluate the diagnostic value of serum cysc for early detection or monitoring treatment of kid...

abstract background: correction of the uremic state by a functioning allograft often restores fertility in women of reproductive age. the rate of fertility significantly differs between industrial countries, developing and middle east countries. on the other hand the results of pregnancy in kidney transplantation (ktp) patients are significantly better than hemodialysis patients, and pregnancy ...