quinolone antibacterials are one of the most important classes of pharmacological agents known as potent inhibitors of bacterial dna gyrase and topoisomerase iv that efficiently inhibit dna replication and transcription by generating several double-stranded dna break. some quinolone derivatives demonstrated inhibitory potential against eukaryote topoismarase ii and substantial dose-dependent cy...

background :    klebsiella pneumoniae is among the most common and significant agents of community and hospital-acquired infections. plasmid mediated quinolone resistance (pmqr) was increasingly identified in enterobacteriaceae family worldwide. plasmid-mediated quinolone resistance (pmqr) was first reported in 1998 from a klebsiella pneumoniae isolate in the usa. till date, five qnr proteins h...

aim : the aim of this study was to evaluate the likelihood ratio and frequency of dq2 and dq8 in iranian patients with celiac disease (cd). background : the hla dq2 and hla dq8 are the important mediators in the development of celiac disease. a few studies evaluated the frequency of hla dq2 and hla dq8 haplotypes among the iranian population with low sample size. patients and methods : in this ...

â â â â â â â â â  the inner meaning of the holy quran â  â  hamid ahmadian * â â â abstractâ  the inner self (‘batin’) in the quran is set in opposition to the outer appearance (‘zaher’). ‘batin’ may have a variety of interpretations the most well-known of which are intended to be documented in this paper. different interpretations of ‘batin’ based on different opinions are as ...

â â â â â  features of gibranian utopia in his literary works â  â sardar aslani * â  â abstractâ  every thinker and man of letters who pursues a goal in his or her works has a utopia. after introducing utopia by plato, farabi and st. augustine, gibran khalil gibran established the foundations of his own particular utopia. the features of his utopia are as follows: 1) freedom 2) kindness 3) jus...

among various types of cities, mining cities have special features including a high concentration of industrial activities associated with the exploration, extraction, refining, processing and export of groundwater resources, the risk of reduction and termination of non-renewable resources, high degree of environmental pollution, high production of domestic and industrial waste and social issue...

abstract since 1960s with sudden and multiple increase in oil revenues and its supremacy over other economic sectors in national income, iranian government officially transformed to a rentire state which seems still is and tend to be in predictable  future. the above mentioned phenomenon caused radical changes in, government size and structures, inflation increase and forming a new and unique k...

most accidents happens because of lack of visibility and not driver’s reaction on time whenan accident occurs. increasing required time for driver’s reaction caused to decreasingaccidents on roadways .intelligent vehicle networks brings enough time for reaction by sendingalert and alternate messages to vehicles on roadway. main propose in this paper is aroundmodulation on reception interval saf...

background and aim: kelussia odoratissima mozaff. is an iranian endangered endemic plant which widely used in the central zagros region of iran as spice and medicinal herb for inflammatory and cardiovascular purposes. the aim of this study was to assess the essential oil compositions of birahgan ecotype of k. odoratissima in chaharmahal and bakhtiari province.methods: this is a fundamental rese...