background & objective: outpatient surgery can be performed by general or spinal anesthesia. spinal anesthetic drugs have side effects. many anesthesiologists choose general anesthesia, because of its relative predictability and to avoid undesirable side effects associated with spinal anesthesia. for example lidocaine is frequently associated with transient neuroligic symptoms (tns). bupivacain...

abstract a poet, author, statesman, and eminent social figure under the ottoman empire, ma'ruf rosafi, lived in a period when ignorance, poverty, and disease had overshadowed the country. obviously, literature in late 19th century and early 20th century witnessed a rise and boom which included political, social, and cultural issues. and it was poetry that could yield positive effects in th...

objectives: different chelators may be used during root canal treatment, offering various advantages including lubricant effect inside the canal and smear layer removal. however, chelator residues in narrow root canals can lead to apical microleakage. the aim of this in-vitro study was to compare apical microleakage following the use of three root canal chelators via fluid filtration method in ...

introduction: in the present study, the effects of oral morphine consumption in pregnant female rats on the amygdaloid complex development in the embryos were investigated. methods: female wistar rats weighing 250-300 g (n=15) were divided into control (n = 8) and experimental groups (n = 7). the experimental group received morphine (0.05 mg/ml) in their tap water. on the 19th day of pregnancy,...

introduction: previous studies have shown that stimulation of lateral hypothalamus (lh) produces antinociception. orexin-a (oxa) receptor is strongly expressed in the nucleus locus coeruleus (lc) and orexinergic fibers densely project from lh to lc. in this study, we assessed the role of lc and its oxa receptors in antinociceptive response induced by lh chemical stimulation in the rat. methods:...

introduction: fennel is rich in phytoestrogens and is used for estrogen deficiency disorders. estrogens affect anxiety through neurochemical systems such as gaba-a receptors. in this study the effects of fennel on gaba-a and estrogen receptors in anxiety were investigated. methods: adult female wistar rats weighing (180±20 g) were divided into 8 groups. groups received saline, fennel (200, 500,...

Background: Curcumin, extracted from turmeric, represents enormous potential to serve as an anticancer agent. Telomerase is viewed as a prominent molecular target of curcumin, and transforming growth factor-β1 (TGFβ1) has proven to be a major inhibitory signaling pathway for telomerase activity. In the current study, we aimed to explore suppressive effects of nanocurcumin on telomeras...

Objective: Parkinson’s disease (PD) is regarded as the second most common neurodegenerative disease affecting elderly population. There is a tendency toward finding natural cures to suppress the initiation and progression of this disease. Some epidemiological studies indicated lower incidence of PD in populations that consume curry. Curcumin, as the main ingredient of turmeric, has been suppose...