Devices that use a spectral reflectance technique are used to non-invasively measure total bilirubin levels in neonates to monitor the development of hyperbilirubinemia. As a screening technique for the healthy neonate population, these devices provide instantaneous information, may reduce the need of heel-pricks on neonates, and indicate which neonates will need serum bilirubin measurement. Ev...

Reserve albumin binding capacity, salicylate saturation index, and red cell binding of bili-rubin in neonatal jaundice. 105 blood samples from 72 infants, mostly with jaundice due to haemolytic disease, were analysed for reserve albumin binding capacity (HBABA method), salicylate saturation index (SI), and red cell binding of bilirubin. 2 infants with clinical symptoms of bilirubin encephalopat...

We compared results by a simplified colorimetric copper-soap method for serum free fatty acids (Clin, Chem. 19: 419, 1973, modified) with those by a gas--liquid chromatographic method. The modified method requires only 100 microliters of sample, its standard curve is linear from 0.1 to 4.0 mmol/L (reference interval for adults: 0.2 to 0.8 mmol/L), and it is suitable for use with newborns. Compa...

The aim of this study is to identify some traditional practices used for the newborn babies in Turkey and to discuss the possible effects of these practices upon the health of the babies. The traditional care practices (salting, swaddling, holluk, starting breastfeeding late, practices against newborn jaundice, making the forties, etc.) reported to be most prevalent between January 2008 and Oct...

BACKGROUND/AIM Prematurity is a significant risk factor for developing unconjugated hyperbilirubinemia. This study investigated the current approach to managing hyperbilirubinemia in preterm newborns in Turkey. MATERIALS AND METHODS A study-specific questionnaire on the management of jaundice in preterm infants was sent to 100 level III neonatal intensive care units in Turkey. RESULTS Respo...

BACKGROUND Transcutaneous bilirubinometry is widely used to predict hyperbilirubinemia by using several devices. The aim of this study was to compare the predictive ability of BiliCheck vs JM-103 in identifying neonates not at risk of significant hyperbilirubinemia, putting the data obtained with the two instruments on our transcutaneous bilirubin nomogram built with the BiliCheck. METHODS Tr...

Curcumin has a wide spectrum of pharmacological activities, including antioxidant, anti-inflammatory, antimicrobial, and anticancer properties. Recently, its potential as effective chemoprevention against cholangiocarcinoma, a highly malignant tumor of the bile duct with limited therapeutic options, was reported. The purpose of the present study was to investigate the contribution of multidrug ...

The accuracy of transcutaneous bilirubin (TcB) measurements obtained with a Bilicheck device in 70 preterm neonates before phototherapy and during phototherapy from the exposed and unexposed skin of the forehead (under the eye patch) was evaluated by comparing the TcB with the total serum bilirubin (TSB) that was performed within +/- 30 minutes of the TcB measurements. The correlation and propo...

OBJECTIVE To assess the utility of 24 and 48 hours transcutaneous bilirubin (TcB) index for predicting subsequent significant hyperbilirubinemia in healthy term neonates. METHODS TcB indices were obtained for healthy, breastfed, term AGA newborns at 24 +/- 2, 48 +/- 2 and subsequently at intervals of 24 hours. Neonates with illness, on treatment and positive Direct Coomb's test were excluded....

extreme lethargy, with enlargement of liver and spleen, and ensuing severe anaemia if the infant survives the first few days. Hampson (1928) reported a series of these cases with 80 per cent, mortality rate. The surviving infants were frequently found to have cirrhosis of the liver and neurological signs of basal ganglia damage, termed kernicterus. Congenital Anaemia is a rarer manifestation, w...