objective: alpha-thalassemia is one of the most prevalent hemoglobin disorders in the world and it is a common hereditary condition caused by deletion of one or more α-globin genes. common α-thalassemia deletions like 3.7 kb, 4.2 kb, 20.5 kb and med can be detected by multiplex pcr. there are, however, some unknown deletions that can not be detected by the mentioned method or even by direct dna...

to investigate uterine fluid and serum calcium (ca) and magnesium (mg) variations during the estrus cycle in water buffaloes, 71 genital tracts and blood samples were collected from the abattoir in urmia. the phase of the estrous cycle was determined by examining ovarian structures. 18 animals were pro-estrous, 15 estrous, 16 met-estrous and 22 diestrous. the uterine fluid was collected by gent...

the aim of this investigation was to study macroscopic and microscopic structures of ovaries in barbus grypus of karoon river and their changes during annual maturation cycle. for this purpose, 120 adult  b.grypus with a mean weight of 835.0 to 1012.0 g, were caught from karoon river and transferred alive to the laboratory. after biometrical studies, the weights and morphological appearances of...

introduction citrullinemia is a defect in the urea cycle that causes ammonia to accumulate in the blood. we describe the anesthetic management of a patient with citrullinemia, who experienced an unexpected 10 day hospital admission. case presentation we anesthetized a 3.5 year-old boy with citrullinemia who was scheduled for a dentistry procedure. perioperative precautions included minimizing f...

shirbot ( barbus grypus ) is one of the species in south and southwest of iran which is greatly favorable to residents of the region. unfavorable ecological conditions in habitat of this species and overfishing have led to the reduction of the population of shirbot. therefore, to restore the natural stock of this species, identifying its reproductive cycle associated with its habitat is of a gr...

the transcriptional factor oct4 regulates pluripotency of stem cells and has an important role during oocyte growth. whereas, its role has remained ambiguous in ovarian tissue during reproductive cycle. therefore, this study was aimed to investigate the expression patterns of oct4 in mouse ovaries during the normal estrous cycle. adult national medical research institute mice were classified as...

background: receptor for hyaluronic acid mediated motility (rhamm) has intracellular and extracellular functions. in this study, we focus on the expression of rhamm in the rat uterus during estrous cycle and implantation period. methods: the female adult rats were divided into six groups following estrous cycle determination (n=36). the utreri of rats were collected according to estrous cycle p...

human immunodeficiency virus (hiv) transactivator tat is a potent activator of both viral and cellu lar genes. tat has also been implicated in the development of aids-related malignancy. here, we show that tat physically and functionally is able to sequester the cell cycle check point protein p53. this sequestration results in non-functional promoter activity of cyclin-dependent kinase/cyclin i...

introduction: in female rats sensitivity to antinociceptive treatment varies during estrous cycle stages. the role of gaba through gabab receptor in nociception has been established. the aim of the present study is to investigate the effect of intercerebroventicular injection of gabab receptor agonist (baclofen) and gabab antagonist (cgp35348) on pain sensitivity during different stages of estr...