OBJECTIVE The efficacy of anti-tumor necrosis factor therapies in rheumatoid arthritis has been demonstrated in randomized clinical trials. The purpose of the present study was to evaluate the effectiveness of these agents for the treatment of rheumatoid arthritis in a real-world setting. METHOD This retrospective chart review included patients from 6 clinics in the United States. Eligibility...

BACKGROUND First metatarsophalangeal joint (MTPJ) mobility is commonly assessed by its angular displacement (joint angle) or subjectively rated as 'hypermobile', 'normal' or 'stiff' by a clinician. Neither of these methods is ideal because displacement alone does not take into account the force required to displace the joint and subjective evaluation is not always reliable. This study presented...

The paper focuses on the stiffness modeling of robotic manipulators with gravity compensators. The main attention is paid to the development of the stiffness model of a spring-based compensator located between sequential links of a serial structure. The derived model allows us to describe the compensator as an equivalent non-linear virtual spring integrated in the corresponding actuated joint. ...

This paper presents the Double Actuator Joint Mechanism, a novel mechanism for robots to generate human-like motion. The mechanism is based on the idea of the equilibrium trajectory hypothesis, a hypothesis that multi-joint limb movements are achieved by shifting the limbs equilibrium positions defined by neuromuscular activity. The magnitude of force exerted on the arm depends on the differenc...

This paper presents a mechanical system with a similar configuration to a human musculo-skeletal system for use in anthropomorphic robots or as artificial limbs for disabled persons. First, a mechanical module called ANLES (Actuator with Non-Linear Elasticity System) is introduced. There are two types of ANLES: the linear-type ANLES and rotary-type ANLES. They can be used as a voluntary muscle ...