Recently, large scale genome-wide association study (GWAS) meta-analyses have boosted the number of known signals for some traits into the tens and hundreds. Typically, however, variants are only analysed one-at-a-time. This complicates the ability of fine-mapping to identify a small set of SNPs for further functional follow-up. We describe a new and scalable algorithm, joint analysis of margin...

Although collective cell motion plays an important role, for example during wound healing, embryogenesis, or cancer progression, the fundamental rules governing this motion are still not well understood, in particular at high cell density. We study here the motion of human bronchial epithelial cells within a monolayer, over long times. We observe that, as the monolayer ages, the cells slow down...

We consider the problem of establishing jam-resistant, wireless, omnidirectional communication channels when there is no initial shared secret. No existing system achieves this. We propose a general algorithm for this problem, the BBC algorithm, and give several instantiations of it. We develop and analyze this algorithm within the framework of a new type of code, concurrent codes, which are th...

local area network, LAN, real-time, CSMA/CD, ethernet, delay-sensitive This paper suggests a CSMA/CD compatible MAC protocol for real-time transmissions in a shared Home or Small Office Local Area Network. The new MAC is based on the distributed assignment of special TAG numbers to the stations transmitting real-time traffic. These TAG numbers determine a Round Robin order of transmissions amon...

When a granular material is impacted by a sphere, its surface deforms like a liquid yet it preserves a circular crater like a solid. Although the mechanism of granular impact cratering by solid spheres is well explored, our knowledge on granular impact cratering by liquid drops is still very limited. Here, by combining high-speed photography with high-precision laser profilometry, we investigat...

Introduction. Undernutrition in children is a major public health concern in Pakistan. A number of interventions which focused only on providing nutrient supplementation have failed to change child undernutrition status during the last 2 decades. The present study aimed to assess the impact of nutrition education on the nutritional status of children living in resource-limited environments. Met...

In this paper, a minimalist, completely distributed freeway traffic information system is introduced. It involves an autonomous, vehicle-based jam front detection, the information transmission via inter-vehicle communication, and the forecast of the spatial position of jam fronts by reconstructing the spatiotemporal traffic situation based on the transmitted information. The whole system is sim...

This paper presents an event-driven way finding algorithm for pedestrians in an evacuation scenario, which operates on a graph-based structure. The motivation of each pedestrian is to leave the facility. The events used to redirect pedestrians include the identification of a jam situation and/or identification of a better route than the current. This study considers two types of pedestrians: fa...

In this paper we present Jam, an extension of the Java language supporting mixins, that is, parametric heir classes. A mixin declaration in Jam is similar to a Java heir class declaration, except that it does not extend a fixed parent class, but simply specifies the set of fields and methods a generic parent should provide. In this way, the same mixin can be instantiated on many parent classes,...

Maintenance works on high-ways usually require installation of bottlenecks that disturb traffic. The article presents a new mathematical model for analysis and forecasting of traffic jam evolution in front of a bottleneck. The model is comprised of two partial differential equations for the mean velocity and density of cars. The first equation describes relaxation of velocity to its equilibrium...