نتایج جستجو برای: isotope effect
تعداد نتایج: 1670266 فیلتر نتایج به سال:
Deuterium isotope effects were evaluated as a strategy to optimize the pharmacokinetics of 7-(3,5-dimethyl-1H-1,2,4-triazol-1-yl)-3-(4-methoxy-2-methylphenyl)-2,6-dimethylpyrazolo[5,1-b]oxazole (NVS-CRF38), a novel corticotropin-releasing factor receptor 1 (CRF1) antagonist. In an attempt to suppress O-demethylation of NVS-CRF38 without losing activity against the CRF1 receptor, the protons at ...
Interaction of fast neutrons with oxygen atoms of cooling water in reactor core leads to the production of 16N isotope which emits 6.13 MeV gamma ray. A system is developed to measure the 16N gamma ray activity using a5.08cm ×5.08cm NaI(Tl) detector. A suitable electronic system is used to count 16N gamma rays in different reactor powers in order to calibrate the 16N system in terms of reacto...
Pd–Ag alloys are largely used as hydrogen separation membranes and, a consequence, the Pd–Ag–H system has been intensively studied. On contrary, fewer information is available for Pd–Ag–D system; thus, aim of this work to improve knowledge isotope effect on commercial Pd77Ag23 alloy, especially temperature above 200 °C. In particular, deuterium absorption measurements carried out in alloy range...
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