نتایج جستجو برای: isoprostane
تعداد نتایج: 1133 فیلتر نتایج به سال:
BACKGROUND There is limited literature on the contributors to isoprostane metabolite 2,3-dinor-5,6-dihydro-15-F(2t)-isoprostane (15-F(2t)-IsoP-M) compared with F(2)-isoprostanes (F(2)-IsoPs) as an oxidative stress biomarker. OBJECTIVE The objective of this study was to investigate whether plasma concentrations of antioxidants, urinary excretion rates of polyphenols, and antioxidants in food a...
OBJECTIVE Myocardial ischemia and reperfusion induced by cardioplegic arrest subjects the heart to free radical-mediated stress. The purpose of our study was to investigate the effect of cardioplegia-induced ischemia and reperfusion on myocardial formation and distribution of (1) nitrotyrosine as an indicator for peroxynitrite-mediated tissue injury resulting from increased nitric oxide release...
b a ckground: to compare the oxidative stress (os) factors in obese and non- obese subjects with type 2 diabetes (t2d) and to evaluate the interaction between the apolipoprotein a-ii (apo a-ii) - 265t > c polymorphism and body mass index (bmi) on os factors. m ethods : in this comparative cross-sectional study, 21 diabetes centers in tehran, iran were studied. 180 patients with t2d were divide...
Lipase B from Candida antarctica (CALB) has been selected as the most suitable enzyme to catalyze the regioselective monoacetylation of 1,5-diol isoprostane intermediate, using vinyl acetate as an acyl transfer reagent in THF. We next applied this reaction on linear 2-substituted, 2,2'-disubstituted-1,5-pentanediols, and cyclic 2,3-disubstituted-1,5-pentanediols. To rationalize the regioselecti...
Isoprostanes are liberated when reactive oxygen species (ROS) mediate the peroxidation of arachidonic acid or other polyunsaturated fatty acids. Because exposure to ROS is associated with tissue damage in the lung, we examined whether exposure to isoprostanes elicited a response in airway epithelial cells, potentially implicating isoprostane production in the epithelial response to oxidant stre...
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