نتایج جستجو برای: ischemic kidney injury
تعداد نتایج: 573979 فیلتر نتایج به سال:
BACKGROUND Kidney transplantation (ktx) in mice is used to learn about rejection and to develop new treatment strategies. Past studies have mainly been based on histological or molecular biological methods. Imaging techniques to monitor allograft pathology have rarely been used. METHODS Here we investigated mice after isogenic and allogenic ktx over time with functional MRI with diffusion-wei...
Despite the high prevalence of acute kidney injury (AKI) and its association with increased morbidity and mortality, therapeutic approaches for AKI are disappointing. This is largely attributed to poor understanding of the pathogenesis of AKI. Heparanase, an endoglycosidase that cleaves heparan sulfate, is involved in extracellular matrix turnover, inflammation, kidney dysfunction, diabetes, fi...
Hydrogen sulfide (H2S) has long been recognized as a putrid, toxic gas. However, result of intensive biochemical research in the past two decades, H2S is now considered to be third gasotransmitter alongside nitric oxide (NO) and carbon monoxide (CO) mammalian systems. H2S-producing enzymes are expressed all organs, playing an important role their physiology. In kidney, critical regulator vascul...
The artherosclerosis of the arteria renalis is typically limited to the proximal third of the artery. The morphological charcteristics, complications (thrombosis, emboli, aneurysm) as well as the etiology and pathogenesis are the same as in artherosclerosis of the aorta. The frequency is age dependent and it is more common in males. Stenosing artherosclerosis was seen in 5% of cases in unselect...
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