BACKGROUND Functional gastrointestinal disorders and fatigue may follow acute infections. This study aimed to estimate the persistence, prevalence, and risk of irritable bowel syndrome and chronic fatigue 6 years after Giardia infection. METHODS We performed a controlled prospective study of a cohort of 1252 individuals who had laboratory-confirmed Giardia infection during a waterborne outbre...

BACKGROUND Zamifenacin is a new potent gut M3 selective muscarinic antagonist developed for possible use in irritable bowel syndrome. METHODS In this multicentre, double-blind, parallel group, placebo-controlled study, the effect of a single dose of zamifenacin 10 mg or 40 mg on both fasting (30 min) and fed (60 min) colonic motor activity was assessed in 36 patients with irritable bowel synd...

The present study is to determine the prevalence and implication of coeliac disease (CD) among adult Saudis and compared to those with diagnosed irritable bowel syndrome. This prospective study was conducted among 980 adults. Out of that, 482 subjects (staff and students of Riyadh Health Science College) were designated as control cohorts for undetected coeliac disease. Furthermore, another con...

background: irritable bowel syndrome (ibs) is a chronic functional bowel disorder that up to 20% of the population is suffering from it. also benign prostatic hyperplasia (bph) is a common problem that approximately 90 percent of men may be affected by this condition until the eighth decade of their life. prostatectomy as a surgery and pelvic intervention can cause ibs. methods: it was a case-c...

BACKGROUND Irritable bowel syndrome (IBS) is a common gut problem that interferes with many people's enjoyment of life. OBJECTIVE Irritable bowel syndrome (IBS) is a common gut problem that interferes with many people's enjoyment of life. DISCUSSION The underlying pathophysiology of IBS is not yet fully understood. People's experience of IBS can fluctuate over time and various bowel symptom...

An appreciable proportion of the general population have the irritable bowel syndrome but do not report it. Results of psychological assessments showed that outpatients with the syndrome and non-reporters of it were psychologically similar, but both groups showed more somatic distress than normal controls. Anxiety, depression, obsessive compulsion, and interpersonal sensitivity were similar in ...

BACKGROUND The effect of low dose radiation on immune system is shown. Ionizing radiation can affect cytokine production and polarization of T helper cells. OBJECTIVE The current study focused on ionizing radiation in Ukrainian children residing in a contaminated area with clinical irritable bowel syndrome. METHOD Our study included 75 rural children population aged 4-18 yrs, who lived in a...

Some women with irritable bowel syndrome date the onset of symptoms to previous hysterectomy. To assess prospectively the incidence of gastrointestinal symptomatology arising de novo after hysterectomy, and to study the effect of surgery on pre-existing symptoms, 205 women completed a symptom questionnaire before and six weeks and six months after surgery. Beforehand, symptoms suggestive of irr...