Agrowing body of evidence suggests that endothelial dysfunction is associated with cardiovascular events. Endothelial dysfunction can be regarded as a syndrome that exhibits systemic manifestations associated with significant morbidity and mortality. The concept of endothelial dysfunction should be extended beyond the conduit vessels into the vascular wall and even to the bone marrow and the pr...

anterior megalophthalmos is a developmental anomaly of the anterior ocular segment. this is an x-linked recessive disease and manifests as bilateral enlarged corneas, open iridocorneal angle, hypoplastic iris and dislocation and opacification of an apparently small lens. we have also observed obvious vitreoretinal degeneration in our patients. what may threaten visual acuity later is an open an...

Anterior megalophthalmos is a developmental anomaly of the anterior ocular segment. This is an X-linked recessive disease and manifests as bilateral enlarged corneas, open iridocorneal angle, hypoplastic iris and dislocation and opacification of an apparently small lens. We have also observed obvious vitreoretinal degeneration in our patients. What may threaten visual acuity later is an op...

Hantavirus cardiopulmonary syndrome (HCPS) is a severe respiratory illness primarily associated with microvascular endothelial changes, particularly in the lungs. However, role of pulmonary epithelium HCPS pathogenesis remains unclear. This study explores potential soluble Receptors for Advanced Glycation End-products (sRAGE) as biomarker assessing epithelial damage HCPS, challenging prevailing...