نتایج جستجو برای: ipi
تعداد نتایج: 1246 فیلتر نتایج به سال:
We characterize the interplay between collection and lowpower operation by studying the joint impact of the offered load and the Low Power Listening sleep time setting on the duty-cycle distribution in a large-scale sensor network testbed. Collection services must be able to work on top of a low-power MAC. The Collection Tree Protocol (CTP) [1] has been shown to perform very well on top of Box-...
increasing in concentration of heavy metals such as lead, cadmium, nickel, chromium and zinc cause considerable harmful effects on soil and environment. these elements are also hazardous to health of humans and wildlife. petrochemical plants and refineries pollution increase the amount of carcinogenic and tratogenic compounds in environment. the main goal of recent paper is the studying of soil...
BACKGROUND Primary bone lymphoma (PBL) is a distinct clinicopathological entity. Although PBL has been reviewed in several small studies, few reflect recent improvements in primary treatment. METHODS We used the British Columbia Cancer Agency Lymphoid Cancer Database to identify all patients with PBL (1983-2005). All were staged in a uniform manner and treated with era-specific protocols. R...
Background Central nervous system (CNS) relapse of diffuse large B-cell lymphoma (DLBCL) is associated with a dismal prognosis. Here, we report an analysis of CNS relapse for patients treated within the UK NCRI phase III R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone) 14 versus 21 randomised trial. Patients and methods The R-CHOP 14 versus 21 trial compared R-C...
Ipilimumab (IPI) blocks CTLA-4 immune checkpoint resulting in T cell activation and enhanced antitumor immunity. IPI improves overall survival (OS) in 22% of patients with metastatic melanoma (MM). We investigated the association of CTLA-4 single nucleotide variants (SNVs) with best overall response (BOR) to IPI and OS in a cohort of 173 MM patients. Patients were genotyped for six CTLA-4 SNVs ...
BACKGROUND A growing number of proteins, including ion transporters, have been shown to interact with Cystic Fibrosis Transmembrane conductance Regulator (CFTR). CFTR is an epithelial chloride channel that is involved in Cystic Fibrosis (CF) when mutated; thus a better knowledge of its functional interactome may help to understand the pathophysiology of this complex disease. In the present stud...
Malignant pleural mesotheliomas (MPMs) are aggressive and often unresectable. In the past, chemotherapy was standard for palliation. Recently, immunotherapy with nivolumab ipilimumab (nivo+ipi) approved. This study evaluated cost-effectiveness of nivo+ipi versus (with without bevacizumab) Swiss patients unresectable MPM, overall by histological subtype. We developed a three-state Markov cohort ...
Purpose The measure of companies' Innovation Performance is fundamental for enhancing the value and decision-making processes firms. purpose this paper to present a new Performance, called Patent Index (IPI), which makes it possible quantitatively summarize different aspects firms' innovation. Design/methodology/approach In order define IPI, secondary source, i.e. patent data, has been used. fi...
BACKGROUND Due to superior results observed with the addition of rituximab into treatment of patients with the diffuse large B-cell lymphoma (DLBCL),the R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone) regimen and its variants became the standard initial treatment of these patients. However, the treatment recommendations are based on results of clinical studies w...
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