نتایج جستجو برای: ion channel

تعداد نتایج: 404687  

2012
James E. Reeve Michael M. Kohl Antonio Rodríguez-Moreno Ole Paulsen Harry L. Anderson

We have previously synthesized a caged form of the use-dependent N-methyl-D-aspartate (NMDA) receptor ion channel blocker MK801 and used intracellular photolysis of this compound to demonstrate the subcellular location of NMDA receptor ion channels involved in synaptic plasticity. Here, we discuss considerations regarding the choice of caging molecule, synthesis and the potential uses for caged...

Journal: :Journal of Synthetic Organic Chemistry, Japan 1995

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2011
Mehabaw G Derebe David B Sauer Weizhong Zeng Amer Alam Ning Shi Youxing Jiang

Selective ion conduction across ion channel pores is central to cellular physiology. To understand the underlying principles of ion selectivity in tetrameric cation channels, we engineered a set of cation channel pores based on the nonselective NaK channel and determined their structures to high resolution. These structures showcase an ensemble of selectivity filters with a various number of co...

Journal: :Biochimica et Biophysica Acta (BBA) - Biomembranes 2002

Journal: :Nucleic Acids Research 1999

Journal: :Current Research in Neuroscience 2010

Journal: :International Journal of Molecular Sciences 2019

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