background: iodine deficiency elimination program has begun since two decades ago in iran. this study was performed to evaluate the adequacy of iodine supplementation after 17 years of national salt iodization in the kermanshah province. methods: in this cross-sectional study 1200 schoolchildren aged 8 to10 year-old from kermanshah province were randomly selected and evaluated in 2007. goiter p...

BACKGROUND Monitoring iodine status during pregnancy is essential to prevent iodine-related disorders. The objectives of this study are to estimate iodine intake and excretion, to assess their association and to evaluate the compliance of the recommendations in a multicentre cohort of pregnant women. METHODS Cross-sectional data on maternal iodine nutritional status, compiled between weeks 8 ...

Oral iodized oil is the major alternative to iodized salt for correcting endemic iodine deficiency. This study responds to a need for better guidelines in its use. Schoolchildren, aged 6-11 yr, from a severely iodine-deficient area of Algeria received iodized poppy seed oil (Lipiodol) in a single oral dose containing 120, 240, 480, or 960 mg iodine (groups A-D) or in an im injection of 480 mg i...

BACKGROUND/METHODS In Germany, iodine deficiency is common. In a representative group of 2,500 Germans (age >13 years), using a specially designed food questionnaire, the iodine intake was calculated. In addition, iodine and creatinine concentrations in spot urine samples were determined in three groups with a possibly increased risk of iodine deficiency (769 conscripts, 886 pairs of mothers an...

OBJECTIVE In NOD.H2h4 mice, high dietary iodine intake has been known to cause iodine-accelerated spontaneous autoimmune thyroiditis (ISAT) via an unknown mechanism. The aim of the study was to examine whether the NOD.H2h4 genetic background predisposes to enhanced iodine organification in thyroglobulin (Tg), a target autoantigen in ISAT. DESIGN To avoid issues associated with an ongoing anti...

OBJECTIVE To examine the importance of iodine nutrition during pregnancy. DESIGN Review of existing literature of iodine in pregnancy. SETTING Population surveys and metabolic studies. SUBJECTS Pregnant women. RESULTS The main changes in thyroid function associated with pregnancy are due to an increase in hormone requirements that begin in the first trimester of gestation. This increase...

Adequate iodine is important during pregnancy to ensure optimal growth and development of the offspring. We validated an iodine-specific FFQ (I-FFQ) for use in Australian pregnant women. A forty-four-item I-FFQ was developed to assess iodine intake from food and was administered to 122 pregnant women at 28 weeks gestation. Iodine supplement use was captured separately at 28 weeks gestation. Cor...

Some years ago Marine and Feiss (1) and Marine and Rogoff (2, 3) first performed experiments which leave little doubt as to the ability of the dog’s thyroid gland, especially when hyperplastic, to bind iodine almost instantaneously. Marine and Feiss (1) carefully perfused the surviving thyroid gland with fluid containing iodine as KI. They found that after 1 hour a considerable amount of iodine...

BACKGROUND Widespread subclinical iodine insufficiency has recently been reported in Europe, based on urinary iodine using World Health Organization/Food and Agriculture Organization criteria, in particular among young women. Although urinary iodine concentration (UIC) is a useful measurement of the iodine status in a population, it does not provide an insight into the habitual iodine intake of...

Iodine is a key component of the thyroid hormones which are crucial for brain development. Adequate intake of iodine in pregnancy is important as in utero deficiency may have lifelong consequences for the offspring. Data on the iodine status of UK pregnant women are sparse, and there are no such data for pregnant women in the South East of the UK. A total of 100 pregnant women were recruited to...