OBJECTIVE To evaluate the efficacy and safety of two low-dose levonorgestrel intrauterine contraceptive systems. METHODS Nulliparous and parous women aged 18-35 years with regular menstrual cycles (21-35 days) requesting contraception were randomized to 3 years of treatment with one of two levonorgestrel intrauterine contraceptive systems: 13.5 mg total content or 19.5 mg total content. The p...

ectopic pregnancy (ep) is a potentially life-threatening condition in which the embryo implants outside the uterine endometrial cavity. abdominal pregnancy is an atypical site wherein the product of conception lies totally outside the reproductive tract. primary abdominal pregnancy is a very rare condition with a high mortality rate. diagnosis is often late or misdiagnosed. the aim of introduci...

background: implantation is considered as the rate-limiting step in success of assisted reproduction techniques, and intrauterine insemination cycles. it might be affected by ovarian superovulation and endometrial local scratching. objective: this study aims to investigate the effect of local endometrial injury on the outcome of iui cycles. materials and methods: in this randomized clinical tri...

The cause of infertility is unexplained in about 22-28% of all infertile couples. The prognosis for spontaneous pregnancy in such couples is better than in those with diagnosed causes of infertility. Traditional treatment options in this group have included expectant management, clomifene citrate, intrauterine insemination with (super ovulation plus intrauterine insemination) or without (intrau...

BACKGROUND Intrauterine device (IUD) migration and colon perforation is a rare but serious complication occurring sometimes years after insertion. Laparoscopic removal of a colon-perforating device is a seldom-used approach. CASE A 35-year-old presented with right upper quadrant (RUQ) abdominal pain one year following intrauterine device (IUD) insertion. Upon vaginal examination, no IUD strin...

Severe intrauterine ischemia is detrimental to the developing brain. The impact of mild intrauterine hypoperfusion on neurological development, however, is still unclear. We induced mild intrauterine hypoperfusion in rats on embryonic day 17 via arterial stenosis with metal microcoils wrapped around the uterine and ovarian arteries. All pups were born with significantly decreased birth weights....

Physicians can obtain fetal heart rate, electrophysiological information, and uterine contraction activity for determining fetal status from an intrauterine catheters electrocardiogram with the maternal electrocardiogram canceled. In addition, the intrauterine catheter would allow physicians to acquire fetal status with one noninvasive to the fetus biosensor as compared to invasive to the fetus...

Objectives: To evaluate the efficacy and safety of an intrauterine system releasing 20μg levonorgestrel per 24 hours in the longterm treatment of heavy menstrual blood loss in women unrelated to intrauterine pathology. Methods: Sixty parous women aged 35-48 years with recurrent menorrhagia participated in this study. Women were followed-up for at least 12 months (12-16 months). The effect on me...