INTRODUCTION Endometrial biopsy is necessary for diagnosing the reason of abnormal uterine bleeding in perimenopausal women. Currently outpatient endometrial biopsy is used for evaluation of abnormal uterine bleeding which is associated with moderate to severe pain. Using lidocaine is one of the procedures which is used for pain relief while biopsy. This study is aimed at comparing the effect o...

Poor fetal growth, also known as intrauterine growth restriction (IUGR), is a worldwide health concern. IUGR is commonly associated with both an increased risk in perinatal mortality and a higher prevalence of developing chronic metabolic diseases later in life. Obesity, type 2 diabetes or metabolic syndrome could result from noxious "metabolic programming." In order to better understand early ...

Studies on fetal undernutrition have generated the hypothesis that fetal programming corresponds to an attempt of the fetus to adapt to adverse conditions encountered in utero. These adaptations would be beneficial if these conditions prevail later in life, but they become detrimental in the case of normal or plentiful nutrition and favor the appearance of the metabolic syndrome. In this articl...

Objective. Determine which factors predict multiple pregnancy in gonadotropin-intrauterine insemination cycles so that cancellation criteria might be developed. Study Design. Retrospective chart review of all patients undergoing gonadotropin-intrauterine insemination over a continuous 36 month period. Results. No factors examined were able to predict the occurrence of multiple pregnancy. Conclu...

Developmental programming of the fetus is a phenomenon that has profound implications for the health of individuals and societies. The term describes the process by which gene expression in the fetus is influenced by the intrauterine environment, such that the structure of major organs and the homoeostatic points of metabolic and endocrine systems are set for life. Through this mechanism, pertu...

background: the association between maternal smoking and poor pregnancy outcome, which is well established in medi­cal literature, has also been corroborated by the results of this study conducted in a turkish hospital. our objective was to investi­gate the effects of cigarette smoking during pregnancy on infant head circumference, height, weight, and body mass in­dex (bmi). methods: in this re...