Paxillin is an adaptor molecule involved in the assembly of focal adhesions. Using different fluorescence fluctuation approaches, we established that paxillin-EGFP is dynamic on many timescales within the cell, ranging from milliseconds to seconds. In the cytoplasmic regions, far from adhesions, paxillin is uniformly distributed and freely diffusing as a monomer, as determined by single-point f...

Aim : To study the features of morpho-functional changes in small intestine mucosa acute adhesive bowel obstruction. Material and methods . The results a comprehensive morphological functional intestine’s mucous membrane 20 patients out 50 with intestinal obstruction were analyzed. Patients underwent resection biopsy from membrane, followed by pathomorphological biochemical examination specimen...

While cell-substrate adhesions that form between the protruding edge of a spreading cell and flat surfaces have been studied extensively, processes that regulate the maturation of filopodia adhesions are far less characterized. Since little is known about how the kinetics of formation or disassembly of filopodia adhesions is regulated upon integration into the lamellum, a kinetic analysis of th...

Adhesion-dependent cells actively sense the mechanical properties of their environment through mechanotransductory processes at focal adhesions, which are integrin-based contacts connecting the extracellular matrix to the cytoskeleton. Here we present first steps towards a quantitative understanding of focal adhesions as mechanosensors. It has been shown experimentally that high levels of force...

Original Article AIMS: To have a comprehensive look at the pelvic organs to know their size, shape, structure, relationship with one another or any pathology of pelvic organs. To assess their role in causing infertility. To assess whether the pathology requires medical or surgical treatment i.e. to formulate the further line of management. METHODS:All infertile patients (primary and secondary) ...

objectives: to investigate the effects of intravenous infliximab in preventing the formation of peritoneal adhesions in an animal model of rat. methods: this was an experimental study being performed in animal laboratory of shiraz university of medical sciences during 2012. sixty albino rats were randomly assigned in to three groups by random design method. the first group received single infli...

context in order to restore ovulation, puncturing ovaries with a needle powered by electricity, under laparoscopic observation, in women with anovulatory infertility with polycystic ovarian syndrome is called laparoscopic ovarian drilling (lod). although peri-adnexial adhesion after the surgery is inevitable, there is lack of evidence regarding the clinical significance. the objective of the pr...

INTRODUCTION Adhesions to mesh/tacks in laparoscopic ventral hernia repair are often cited as reasons not to adopt its evidence-based superiority over conventional open methods. This pilot study assessed the occurrence of adhesions to full-sized Polypropylene and Gore-tex DualMesh Plus meshes and the possibility for adhesion prevention using fibrin sealant. METHODS Two 10-cm to 15-cm pieces ...