objectives: presence/absence of cervical lymph node metastasis plays a critical role in prognosis and survival of patients with oral squamous cell carcinoma (scc). this study was designed to assess the diagnostic accuracy of computed tomography (ct) scan for detection of cervical lymph node metastasis in oral scc in comparison with histopathological analysis after neck dissection methods: in th...

background: this study evaluated the relation between telomere length in lymph node (ln) and prognosis of esophageal squamous cell carcinoma (escc).  materials and methods: lns collected from 50 patients were assessed by pathological examination and quantitative reverse transcription polymerase chain reaction (qrt-pcr), which was used for detecting telomere length. the relation between clinical...

Background: Esophageal carcinoma is one of the most lethal gastrointestinal (GI) malignant tumors worldwide.  The disease is known to have a high incidence in northern Iran; however, its condition in the South is not much clear. Objective: In this retrospective study we investigated the epidemiology and time trends of esophageal carcinoma in Fars Province, South of Iran. Methods: In a retrospec...

introduction: squamous cell carcinoma (scc) is the most common head and neck malignancy. to decrease the side effects of treatment and mortality from disease relapse, careful staging for the proper treatment plan is necessary. the main purpose of this prospective study is to compare the diagnostic value of computed tomography (ct) and magnetic resonance im-aging (mri) in oral scc and its lymph ...

objective(s) matrix metalloproteinases comprise a family of enzyme that is able to degrade components of extra cellular matrix. there are single nucleotide polymorphisms in the promoter regions of several genes with ability to influence cancer susceptibility. the aim of this study was to analyses association between mmp2 and mmp9 promoter polymorphisms and head and neck squamous cell carcinoma ...

verrucous carcinoma is a unique clinical and pathological entity which has been recognised in the recent years. it is a variant of well-differentiated squamous cell carcinoma which may occur in the larynx; other anatomic locations such as: the oral cavity, anogenital region, and skin may be involved. it accounts for 1-2% of all laryngeal cancers. the clinical, histopathological and biologic fea...

Primary intraosseous squamous cell carcinoma (PIOSCC) is a rare carcinoma, which arises within the jaws without connection to the oral mucosa and presumably develops from a remnant of odontogenic epithelium. We present a case of solid type PIOSCC in a 52-year-old male patient complaining of dull pain on his left lower molar. In this case, early stage PIOSCC mimicking a periapical lesion might l...