BACKGROUND Posterior capsular opacification (PCO) is a common long-term complication of cataract surgery. Intraocular lens design and material have been implicated in influencing the development of PCO. This study evaluated the association of hydrophobic and hydrophilic intraocular lenses on preventing PCO. METHODS Medline, Cochrane, EMBASE, and Google Scholar databases were searched until Au...

Sight threatening immune responses that damage the eye characterize intraocular inflammatory diseases. These diseases including uveitis and age-related macular degeneration are worryingly common and quality of life shattering. Genetic studies in past decades significantly advanced our understanding of the etiology of these devastating diseases. Unfortunately, patient genetics alone failed to ad...

Administration of timolol to one eye is associated with a decrease in intraocular pressure in both eyes. To further investigate this effect the contralateral decrease in intraocular pressure was measured in a three arm crossover study using a 0.1 mg dose of timolol given topically to an eye, a 0.1 mg dose of timolol given lingually, and a placebo given topically. Two hours after topical timolol...

BACKGROUND/AIM It is known that glaucoma is associated with elevated intraocular pressure and obesity, yet the precise etiology remains unclear. The aim of this study was to determine whether there is a potential causality between the volume of retrobulbar adipose tissue and the level of intraocular pressure in obese subjects compared with non-obese. METHODS A total of 100 subjects were divid...

herein we describe a case of intraocular melanoma in a17-year old leukemic patient.   the history, histological findings of the enucleated eye, blood and bone marrow of the patient were investigated. the enucleated eye contained epitheloid cell type melanoma instead of leukemic cell infiltration.  we conclude that intraocular malignant melanoma can occur in acute lymphoblastic leukemia.

PURPOSE To determine whether a new cyclic GMP analog, 2'-O-(4-benzoyl)benzoylguanosine 3',5' cyclic monophosphate (BB-cGMP), significantly reduces intraocular pressure in either normotensive or hypertensive eyes of rabbits. METHODS Intraocular pressure of normal adult rabbits and/or rabbits with alpha-chymotrypsin-induced ocular hypertension was measured after topical application of BB-cGMP f...

AIMS We report the case of a myopic patient who, after intraocular lens transplant in the posterior chamber, suffered elevated intraocular pressure due to pigment dispersion, with recurrent episodes of blurred vision. The patient was treated with a new surgical technique that can avoid potential iridolenticular contact. METHODS Complete ophthalmologic examination and optical coherence tomogra...

OBJECTIVE To evaluate the effectiveness of trabeculectomy trabeculotomy in the reduction of intraocular pressure in patients with primary congenital glaucoma. MATERIAL AND METHODS A pre-experimental before and after study was conducted with several measurements after; patients with intraocular pressure≥21 mmHg were included, of both sexes, and children under six years, which had ​​the trabecu...