The pharmacokinetics of conventional and long-acting oxytetracycline (OTC) formulation were evaluated in sheep at a single dosage of 20 mg-kg-1 body weight (bw). Conventional formulation was injected by intravenous (IV) route and long-acting formulation of oxytetracycline was administered by intramuscular (IM) route. Then blood samples were taken at 0.25, 0.5, 1, 2, 4, 8, 12, 24, 36, 48, 60, 72...

Male albino rats weighing between 150-225 gm fasted over night but freed having water ad libitum were used to assess the diuretic efficacy of intramuscular aminophylline and frusemide separately and concurrently after intraperitoneal 10 ml of distilled water loading. The normal rate of diuretic weight loss was less augmented by aminophylline and more augmented by frusemide. The diuretic respons...

With an agreed success rate of about 85 per cent. the role of oral oxytetracycline hydrochloride in the treatment of non-specific urethritis was firmly established a decade ago. Other oral tetracyclines have proved of similar value. While the results obtained with intramuscular oxytetracycline and other tetracyclines have been comparable, the incidence of pain at the injection site has been suc...

background croup, or acute laryngotracheobronchitis, is the most common cause of upper airway obstruction in children. objectives in this study, the efficacies of intramuscular and oral dexamethasone administration are compared for treatment of croup. patients and methods this is a single-blind randomized trial involving 68 children divided into two groups, the first group received 0.6 mg/kg in...