INTRODUCTION: Many studies have proved the role, efficacy and safety profile of intralesional bleomycin in the management of hypertrophic scars and keloids.1 Liposomes, by virtue of their lipid bilayer, have potential to enhance the delivery of drug to the desired area. Drugs encapsulated in liposomes are expected to be transported without rapid degradation and minimum side effects to the recip...

OBJECTIVE To evaluate the outcome of our experience in the treatment of congenital subglottic hemangiomas. DESIGN Retrospective review of records. SETTING Airway tertiary care service. PATIENTS From 1986 to 2006 we treated 39 pediatric patients affected by congenital subglottic hemangiomas. INTERVENTION Therapeutic choice depended on presentation symptoms and grade of respiratory obstru...

Corticosteroids are potent anti-inflammatory and anti-allergic agents used in the treatment of various inflammatory diseases, including allergic disease. They are frequently considered the therapy-of-choice for many skin diseases. However, allergic reactions caused by corticosteroids have been reported. Among these, delayed reactions to topical steroids are more common, whereas immediate reacti...

introduction: chronic radicular low back pain is a common disease that limits patient’s daily activity. epidural steroid injection (esi) is becoming the mainstay of therapies for radicular low back pain due to contained bulged disc. aim: to determine the effect of adding hypertonic saline to epidural steroid injections to provide pain relief for chronic radiculopathy back pain secondary to fora...

Background: Wart is a common skin disease, and 8% of patients referred to dermatologists suffer from warts. Objective: To compare the efficacy of intralesional injections of bleomycin with normal saline in treatment of common resistant warts on palms and dorsum of hands. Patients & Methods: This study was a double blind, randomized, controlled clinical trial on 34 patients with common war...

Over a 6-year period, we collected data from 256 keloid lesions from 192 patients. The patients were collected from the Barts and The London National Health Service Trust catchment area in East London and the City of London, United Kingdom, and all 192 patients were referred from hospital-based surgical specialties and dermatology to our specialist keloid clinic. In our keloid clinic, we treat ...

UNLABELLED A case of orbital lymphangioma in a 9 year-old female, with proptosis (Hertel= 29 mm), ocular motility restriction, pain and visual loss due to compressive optic neuropathy is described. A magnetic resonance imaging (MRI) exam showed an expansive cystic lesion in the extraconal space of the right orbit, non-infiltrating with intralesional hemorrhage. The patient had no improvement wi...

BACKGROUND Flagellate hyperpigmentation is a well-documented complication of systemic bleomycin sulfate therapy when using doses of 100 U or more as an antineoplastic agent. Two cases occurred after using systemic doses from 15 to 30 U injected intravenously or intrapleurally; however, it has not been described as a complication following intralesional treatment of verruca plantaris. OBSERVAT...

acute cutaneous leishmaniasis(ACL) is an endemic disease in developing countries.the first line drug for treatment of ACL.according to WHO recommendation,is the pentavalent antimony compounds such as meglumine antimoniate(Glucantime{SB}).high cost ,side effects,multiple injections and incomplete efficacy are limitations of this therapy.we evaluated the efficacy of intralesional(IL) injection of...