Warts are common viral infections of the skin and mucous membranes that caused by human papilloma virus (HPV). prevalent worldwide. Recently, immunotherapy with intralesional antigens or vaccines has been tried for treatment warts encouraging results. It could lead to resolution without any physical changes scarring in addition would augment host response against causative agent. The aim this s...

INTRODUCTION We present a case of lipoatrophy treated successfully with intralesional normal saline injections. Localized lipodystrophy, or lipoatrophy, presents as focal loss of subcutaneous fat with variable overlying skin changes and depth depending on the cause. Lipoatrophy could result from both oral and local intralesional corticosteroid use, with the buttocks and proximal extremities bei...

Cryotherapy has recently been examined as a potential treatment for Alopecia Areata (AA). AA can be managed with intralesional or systemic steroids but relapse rates among those longstanding disease are high. This review serves to describe the existing studies evaluating cryotherapy of and examine comparing steroid injection AA. A systematic literature from 1990 2022 was conducted looking keywo...

R egional chemotherapy usually involves using intra-arterial or intracavitary drug infusion to increase drug concentration within tumor-containing tissue while minimizing systemic toxicity. It has long been used as a treatment modality for various malignancies including melanoma, soft tissue sarcoma, and primary brain tumors. Analogous to regional chemotherapy, intralesional chemotherapy has be...

Background. Topical treatment of cutaneous leishmaniasis is an attractive alternative avoiding toxicities of parenteral therapy while being administered through a simple painless route. Recently liposomal formulations of amphotericin B have been increasingly used in the treatment of several types of leishmaniasis. Aims. The efficacy of a topical liposomal amphotericin B formulation was compared...

Talimogene laherparepvec is a herpes simplex virus-1-based intralesional oncolytic immunotherapy and is the first oncolytic virus to be approved in Europe. It is indicated for the treatment of adults with unresectable melanoma that is regionally or distantly metastatic (stage IIIB, IIIC, and IVM1a) with no bone, brain, lung, or other visceral disease. Talimogene laherparepvec is a genetically m...

Warts are among the most common skin diseases especially in children between the ages of 12-16 years. Usually plantar and periungual lesions are resistant to traditional treatments and cause a lot of trouble for patients. The aim of this study was to evaluate therapeutic effects of intralesional Bleomycin injection. This study was performed on 38 cases of recalcitrant warts. All the lesions dis...