It is widely known that metformin reduces the levels of circulating pro-coagulant factors and improve fibrinolytic activity in type 2 diabetes when used in therapeutic doses. Potential alterations of coagulation have not been reported in patients with metformin intoxication. We evaluated certain components of the coagulation system in a patient with metformin intoxication upon admission and aft...

Amanita pantherina poisoning is suspected as the cause of a severe, transient neurological disorder in three 5-week-old German shepherd puppies. There was very strong circumstantial evidence that this mushroom had been eaten, and the signs encountered were similar to those described in confirmed field cases of intoxication in dogs. It was also in many respects consistent with the syndrome seen ...

Granulocyte mobilization into skin abrasions in human volunteers was significantly inhibited by acute alcohol intoxication (45,-800 cells in 8 hr versus 353,000 in normal controls). Alcohol applied locally did not inhibit granulocyte delivery, and protection of the abrasion against heat loss did not reduce the inhibited delivery in intoxicated volunteers. Intoxication inhibited granulocyte adhe...

Amitraz is commonly used in agricultural industries throughout the world as a farm-animal insecticide. Despite its widespread use, amitraz intoxication is extremely rare and mainly occurs through accidental ingestion by young children. Severe, life-threatening amitraz intoxication in adults is very rarely recognized and reported. Described herein is a previously healthy 54-year-old patient who ...

Balance control when standing upright is a complex process requiring input from several partly independent mechanisms such as coordination, feedback and feedforward control, and adaptation. Acute alcohol intoxication from ethanol is recognized as a major contributor to accidental falls requiring medical care. This study aimed to investigate if intoxication at 0.06 and 0.10% blood alcohol concen...

BACKGROUND The continuous exposure to inorganic mercury vapour in artisanal small-scale gold mining (ASGM) areas leads to chronic health problems. It is therefore essential to have a quick, but reliable risk assessing tool to diagnose chronic inorganic mercury intoxication. This study re-evaluates the state-of-the-art toolkit to diagnose chronic inorganic mercury intoxication by analysing data ...

Dr. Colmar Niederstadt, Department of Internal Medicine, Medical University of Lübeck, Ratzeburger Allee 160, D-23538 Lübeck (Germany) From days 4-18 after intoxication, we repeatedly measured the urinary concentration of immunoglobulin G, albumin, < xi-microglobulin and endogenous creatinine clearance (fig. 1). Ethylene glycol itself is probably not nephrotoxic, but in the metabolism of ethyle...

Alcohol-related liver disease is the most common cause of worldwide. The purpose this work establishment influence transcription factor κB on development oxidative-nitrosative stress in rats under conditions chronic alcohol intoxication. experiments were performed 24 male Wistar weighing 180-220 g. animals divided into 4 groups 6 animals: control; animals, which administered NF-κB inhibitor, na...

We discuss a patient with cocaine intoxication in whom the initial presentation was that of asystole and ventricular fibrillation. Cocaine has a direct toxic action on the heart and also sensitizes cardiac tissue to the action of catecholamines. Cocaine intoxication should be considered in any patient with unexplained cardiac arrest or ventricular arrhythmias.

introduction: iran is a young-populated country. loss of consciousness (loc) due to poisoning is a major cause of patients&apos; referrals to emergency departments. it has good prognosis if it is appropriately diagnosed and treated. this study was done to determine the causes of loc in patients hospitalized in poisoning icu of loghman-hakim poison hospital (lhph) from september 23, 2004 to marc...