BACKGROUND Baseline carotid intima-media thickness (IMT) and plaques are considered predictors of cardiovascular events, but whether they maintain predictive value in treated hypertensive patients and whether time-related (or treatment-induced) IMT changes are additional predictors are unknown. METHODS AND RESULTS Analyses were performed of the data from the European Lacidipine Study on Ather...

OBJECTIVE To study the actions of c-Myc gene fragments in restenosis after coronary artery bypass grafting (CABG). MATERIALS AND METHODS A total of 25 healthy pure breeds New Zealand white rabbits were randomly divided into 5 groups according to weight, 5 in each group. The external jugular vein is placed at ipsilateral common carotid artery and sampling at 6h, 2d, 7d, 14d and 28d. The expres...

Intima-media thickening (IMT) in response to hemodynamic stress is a physiological process that requires coordinated signaling among endothelial, inflammatory, and vascular smooth muscle cells (VSMC). Axl, a receptor tyrosine kinase, whose ligand is Gas6, is highly induced in VSMC after carotid injury. Because Axl regulates cell migration, phagocytosis and apoptosis, we hypothesized that Axl wo...

BACKGROUND AND PURPOSE Whether angiotensin-converting enzyme (ACE) inhibitors have any clinically significant antiatherogenic effects in humans remains unproven. We undertook a prospective randomized clinical trial of 98 patients with non-insulin-dependent diabetes mellitus (NIDDM) to examine the efficacy of ACE inhibition with enalapril for preventing intima-media (IM) thickening of the caroti...

The up-to-date data on origin, diagnostic approach and treatment of juvenile systemic scleroderma in the child with disease onset at early age are presented article. value anamnesis clinical data, laboratory instrumental methods investigation, particular, identification immunological markers, ultrasound Doppler scan vessels as well capillaroscopy nail bed covered. main examinations for diagnosi...

BACKGROUND Chronic Obstructive Pulmonary Disease (COPD) is associated with subclinical systemic atherosclerosis and pulmonary vascular remodelling characterized by intimal hyperplasia and luminal narrowing. We aimed to determine differences in the intimal thickening of systemic and pulmonary arteries in COPD subjects and smokers. Secondary aims include comparisons with a non-smokers group; dete...

International Journal of Medicine and Public Health,2022,12,4,165-168.DOI:10.5530/ijmedph.2022.4.30Published:January 2023Type:Original ArticleCarotid Intima-media Thickness is a Sequel Elevated FGF-23 Levels in CKD!Upma Narain, Arvind Gupta, Seema Pandey Upma Narain1,*, Gupta2, Pandey3 1Microbiologist Immunologist, Tejas Microdiagnostics, Prayagraj, Uttar Pradesh, INDIA. 2Department Nephrology,...

BACKGROUND The combined thickness of the intima and media of the carotid artery is associated with the prevalence of cardiovascular disease. We studied the associations between the thickness of the carotid-artery intima and media and the incidence of new myocardial infarction or stroke in persons without clinical cardiovascular disease. METHODS Noninvasive measurements of the intima and media...

OBJECTIVE To determine site specific carotid intima-media thickness: common-carotid artery and carotid bifurcation in hypercholesterolemia patients as a marker for atherosclerosis. METHODS Fifty patients with hypercholesterolemia and twenty controls were selected after getting informed consent regarding the investigation of carotid- intima media thickness by B-mode ultrasound. All the patient...