BACKGROUND: Fenestration is a simple, superior and economic operation than laminectomy microdiscectomy and percutaneous discectomy, which require costly & sophisticated set ups. Fenestration provided the excellent results comparable to laminectomy procedure, and at the same time preserved the spinal stability and provided the early mobility & early return to previous job. To analyses the result...

INTRODUCTION Low back pain is a major economical and social problem nowadays. Intervertebral disc herniation and central degeneration of disc are two major reasons of low back pain that occur because of structural impairment of disc. The intervertebral disc contains three parts as follows : Annulus fibrosus, transitional region, and nucleus pulposus, which forms the central nucleus of the disc....

It is the unique interaction between the solid and fluid components that provide the intervertebral discs the strength and flexibility necessary to bear the physiological loading of the spine. The current research is directed towards developing a numerical model of a lumbar disc including the fluid flow into and out of the intervertebral disc. The presence of the fluid is imperative in order to...

Dogs presented to the Small Animal Hospital of Veterinary Medicine, University of Tehran were included in the present study if spinal or intervertebral disc involvement was suspected. Clinical signs were recorded as well as general information of the patient such as age, breed and sex. Sixty dogs were examined radiographically and two standard orthogonal lateral and ventrodorsal projections wer...

STUDY DESIGN Mechanically induced annular disruption of lumbar intervertebral discs followed by microstructural investigation. OBJECTIVE To investigate the role that elevated nuclear pressures play in disrupting the lumbar intervertebral disc's annulus fibrosus. SUMMARY OF BACKGROUND DATA Compound mechanical loadings have been used to recreate clinically relevant annular disruptions in vitr...

BACKGROUND Magnetic resonance imaging (MRI) studies have shown that gymnasts have a high prevalence of radiological abnormalities, such as intervertebral disk degeneration (IDD) and anterior limbus vertebra (ALV). These 2 abnormalities may coexist at the same spinal level. However, the relationship between IDD and ALV remains unclear. HYPOTHESIS A significant relationship exists between IDD a...

The inter-lamellar connectivity of the annulus fibrosus in the intervertebral disc has been shown to affect the prediction of the overall disc behaviour in computational models. Using a combined experimental and computational approach, the inter-lamellar mechanical behaviour of the disc annulus was investigated under conditions of radial loading. Twenty-seven specimens of anterior annulus fibro...

Lumbar disc herniation is a relatively common disease. Magnetic resonance imaging (MRI) is the firstused diagnostic tool for evaluating spinal pathologies and represents adiagnostic gold standard. However, the diagnosis of intervertebral disc herniation can still be very difficult in some cases, even in this MRI era. Considering that little is known about this area, and to share our experience,...

STUDY DESIGN Matrix protein gene expression was determined for cells of the anulus fibrosus (AF) and nucleus pulposus (NP) regions of the intervertebral disc when cultured in AF or NP cell-conditioned medium. OBJECTIVES To investigate changes in mRNA levels for type I collagen, type II collagen and aggrecan in cells of the AF and NP in response to cell-conditioned medium. SUMMARY OF BACKGRO...

The intervertebral disc is an important mechanical structure that allows range of motion of the spinal column. Degeneration of the intervertebral disc--incited by aging, traumatic insult, genetic predisposition, or other factors--is often defined by functional and structural changes in the tissue, including excessive breakdown of the extracellular matrix, increased disc cell senescence and deat...