79 Abstract: Experimental cages started with a mixture of flies at three different ratios (1:9, 5:5, 9:1) from populations having heterosomal and autosomal sex–determining mechanisms were cytogenetically examined over six generations at two different temperatures (25 °C and 35 °C). In general, there was an increase in the frequency of XX males in all competitive population cages. Abnormal teste...

Disorders of sex development (DSD), previously referred to as intersex disorders, comprise a variety of congenital diseases with anomalies of the sex chromosome, the gonads, the reproductive ducts and the genitalia. DSD is loosely classified into four groups on the basis of histological features of the gonadal tissue: XX-DSD with two ovaries (female pseudohermaphroditism), XY-DSD with two testi...

As shown by DOBZHANSKY and BRIDGES (1928), triploid intersexes in Drosophila may be considered as individuals developing up to a certain moment as males and thereafter as females. The earlier or later occurrence of the turning point in the development of an intersex determines the production of an individual manifesting relatively more male or relatively more female characteristics. If the turn...

When a child is born with ambiguous genitalia it is declared a psychosocial emergency, and the policy first proposed by John Money (Johns Hopkins University) and adapted by the American Academy of Pediatrics (and more broadly accepted in Canada, the U.K., and Europe) requires determination of underlying condition(s), selection of gender, surgical intervention, and a commitment by all parties to...

With her sexual configurations theory (SCT), vanAnders (2015) wants to solve a number of problems with the current conceptualization of sexual orientation as defined by the sex of the partner(s) one is attracted toandhabitually indicatedwith theKinsey score varying from completely heterosexual to completely homosexual. I agree with van Anders that the conventional conceptualization of sexual or...

We investigated the origin of XX sex reversal in the insectivorous mole Talpa occidentalis. Cytogenetic, histological and hormonal studies indicate that all XX individuals analyzed from two different populations are true hermaphrodites, with ovotestes. This suggests that XX sex reversal may be the norm in this species. The intersexes are functional fertile females and the trait is transmitted a...

We estimated cholinesterase (EC 3.1.1.8) activities in erthrocytes and plasma of 443 men, 188 women not taking oral contraceptives, and 70 women who were taking oral contraceptives. Men in the first six decades of life had higher plasma cholinesterase activity than did women who were not taking oral contraceptives, and these women had higher plasma cholinesterase activity than women taking oral...