Epidemiological studies have established a relationship between low levels of serum vitamin D and reduced lung function in healthy adults, and asthma onset and severity in children. However, no study has examined the relationship between vitamin D levels and exercise-induced bronchoconstriction in asthmatic children. We evaluated the relationship between 25-hydroxyvitamin D concentrations and b...

A 60-year-old diabetic woman with stage IV chronic kidney disease and a history of lichen planus presented with chronic intermittent solid food dysphagia for seven years that had worsened over the past year. She had associated dyspeptic symptoms with no other gastrointestinal symptoms. She had been treated with lansoprazole and famotidine, with some improvement in her symptoms. She reported no ...

introduction: ramadan is the 9th  islamic lunar month during which muslims avoid eating and drinking from sunrise to sunset.  the effect of ramadan intermittent fasting on asthma control is controversial.  the aim of this study was to investigate the effects of ramadan fasting on the spirometric variables and clinical symptoms on well-controlled asthmatic patients during ramadan. material and m...

BACKGROUND The human airway is believed to be acidified in asthma. In an acidic environment nitrite is converted to nitric oxide (NO). OBJECTIVE We hypothesized that buffering airway lining fluid acid would decrease the fraction of exhaled NO (F(ENO)). METHODS We treated 28 adult nonsmoking subjects (9 healthy control subjects, 11 subjects with mild intermittent asthma, and 8 subjects with ...

309 Difficult-to-treat Asthma with Idiopathic Chronic Eosinophilic Pneumonia Norbert Pauk, PhD, MD. Department of Pneumology, Faculty Hospital Na Bulovce, 3rd Faculty of Charles University, Prague, Czech Republic. Background: Idiopathic chronic eosinophilic pneumonia (ICEP) is a rare disorder of unknown cause characterised by subacute or chronic respiratory and general symptoms, alveolar and /o...

OBJECTIVES Asthma is one of the more common reasons for children's visits to the emergency departments (EDs). Many studies show that the level of asthma care and self-management in children before an ED visit for asthma is often inadequate; however, most of these studies have been conducted in the inner cities of large urban areas. Our objectives were to describe asthma care and management in c...

BACKGROUND The introduction of component-resolved diagnosis was a great advance in diagnosis of allergy. In particular, molecular allergy techniques allowed investigation of the association between given molecular profiles and clinical expression of allergy. We evaluated the possible correlation between the level of specific IgE (sIgE) to single components of Phleum pratense and clinical issues...

309 Difficult-to-treat Asthma with Idiopathic Chronic Eosinophilic Pneumonia Norbert Pauk, PhD, MD. Department of Pneumology, Faculty Hospital Na Bulovce, 3rd Faculty of Charles University, Prague, Czech Republic. Background: Idiopathic chronic eosinophilic pneumonia (ICEP) is a rare disorder of unknown cause characterised by subacute or chronic respiratory and general symptoms, alveolar and /o...

BACKGROUND Vitamin D has effects on the innate and adaptive immune system. In asthmatic children low vitamin D levels are associated with poor asthma control, reduced lung function, increased medication intake, and exacerbations. Little is known about vitamin D in adult asthma patients or its association with asthma severity and control. METHODS Clinical parameters of asthma control and 25-hy...

309 Difficult-to-treat Asthma with Idiopathic Chronic Eosinophilic Pneumonia Norbert Pauk, PhD, MD. Department of Pneumology, Faculty Hospital Na Bulovce, 3rd Faculty of Charles University, Prague, Czech Republic. Background: Idiopathic chronic eosinophilic pneumonia (ICEP) is a rare disorder of unknown cause characterised by subacute or chronic respiratory and general symptoms, alveolar and /o...