نتایج جستجو برای: interleukin 23

تعداد نتایج: 280903  

Journal: :Infection and immunity 2007
Xiaowen L Rudner Kyle I Happel Erana A Young Judd E Shellito

Host defense mechanisms against Pneumocystis carinii are not fully understood. Previous work in the murine model has shown that host defense against infection is critically dependent upon host CD4(+) T cells. The recently described Th17 immune response is predominantly a function of effector CD4(+) T cells stimulated by interleukin-23 (IL-23), but whether these cells are required for defense ag...

Journal: :iranian journal of allergy, asthma and immunology 0
marjan taherian immunology department, school of public health, tehran university of medical sciences, tehran, iran ali reza razavi immunology department, school of public health, tehran university of medical sciences, tehran, iran maryam izad immunology department, school of medicine, tehran university of medical sciences, tehran, iran rubina boghozian immunology department, school of public health, tehran university of medical sciences, tehran, iran haydeh namdari immunology department, school of medicine, tehran university of medical sciences, tehran, iran mojgan ghayedi immunology department, school of medicine, tehran university of medical sciences, tehran, iran

interleukin (il)-17-producing t helper (th)-17 cells have recently been explained as a distinct population  of  cd4+  t  cells which play an important  role in immunity against infectious agents. establishment of persistent phenotype of th17 cells and recognition of lineage-deviating factors are of most attractive goals in modern researches in immunology. although  il-6  and  tgf-β  are  freque...

2011
Hyun Soo Kim Dongseok Choi Lyndell L. Lim Gopal Allada Justine R. Smith Carrie R. Austin Trudy M. Doyle Kelley A. Goodwin James T. Rosenbaum Tammy M. Martin

Interleukin 23 receptor (IL23R) gene has been reported as a genetic factor strongly associated with inflammatory bowel disease, psoriasis, and ankylosing spondylitis. We investigated the association between IL23R gene single nucleotide polymorphisms (SNPs) and susceptibility to sarcoidosis, including the clinical manifestation of uveitis. Ninety-one sarcoidosis subjects (58 with and 33 without ...

Journal: :Skin therapy letter 2015
Ramya Kollipara Christopher Downing Rachel Gordon Stephen Tyring

In the past three decades, major advances have been made in understanding the pathogenesis of psoriasis. The currently accepted theory is that T-cell mediated immune dysregulation triggers keratinocyte hyperproliferation in psoriasis. Recent research indicates that the Th17/interleukin (IL)-23 pathway plays a prominent role in the amplification phase of psoriasis. The discovery of the Th17/ IL-...

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