This paper presents a study of confidence measure based techniques for detecting phoneme level mispronunciations in utterances from impaired children with neuromuscular disorders. Several different adaptation scenarios are investigated to determine the effects of mismatched speaker characteristics and mismatched task domain on the ability to verify the phoneme level pronunciations. These techni...

A previous study had shown a strong relationship between a variant in factor VII activating protease (FSAP G511E) and advanced carotid atheroma. In-vitro, the variant has reduced fibrinolytic but normal pro-coagulant activity, which may constitute a prothrombotic state. The current study has addressed risk for coronary heart disease in a prospective study of cardiovascular disorders (Northwick ...

SARA is an ongoing research project that investigates in a novel and artistic way the causes for social communication and emotion recognition deficits in children and adolescents with high-functioning autism spectrum disorders (ASD). The novelty of our work resides in the real-time generation and parameterization of emotional facial expressions of virtual characters by means of speed, intensity...

As in many low-income countries, the treatment gap for developmental disorders in rural Pakistan is near 100%. We integrated social, technological, and business innovations to develop and pilot a potentially sustainable service for children with developmental disorders in 1 rural area. Families with developmental disorders were identified through a mobile phone-based interactive voice response ...

Chronic cigarette smoking is associated with adverse effects on cardiac, pulmonary, and vascular function as well as the increased risk for various forms of cancer. However, little is known about the effects of chronic smoking on human brain function. Although smoking rates have decreased in the developed world, they remain high in individuals with alcohol use disorders (AUD) and other neuropsy...

background :comparing computer and internet based instruction with traditional giving lecture would provide enough evidence to identify best teaching practice. in this study, we compared lecture, interactive internet based and computer based learning regarding medical students' knowledge acquisition and satisfaction in teaching pathophysiology of hematology and oncology.   methods : eighty four...

This paper reviews interactive methods for improving the phonetic competence of subjects in the case of second language learning as well as in the case of speech therapy for subjects suffering from hearing-impairments or articulation disorders. As an example our audiovisual feedback software “SpeechTrainer” for improving the pronunciation quality of Standard German by visually highlighting acou...

To examine risk and resilience factors that affect health, lifetime stress exposure histories, dispositional forgiveness levels, and mental and physical health were assessed in 148 young adults. Greater lifetime stress severity and lower levels of forgiveness each uniquely predicted worse mental and physical health. Analyses also revealed a graded Stress × Forgiveness interaction effect, wherei...