The paper aims to investigate the basin of attraction map a complex Vehicle Routing Problem with random walk analysis. (VRP) is common discrete optimization problem in field logistics. In case base VRP, positions one single depot and many customers (which have product demands) are given. vehicles their capacity limits also fixed system objective function minimization length route. literature, a...

A number of factors influence the efficiency, productivity, and welfare of transportation networks. Travel demand, user costs, and facility supply costs equili-brate on various time scales under a set of pricing (taxes and tolls), investment and ownership policies. Two types of equilibria exist in a transportation network, short-run traffic equilibrium and long-run supply-demand equilibrium. Th...

background it seems that depot-medroxyprogesterone acetate (dmpa) use can have an effect on a woman’s oral health, and cause periodontal changes in adult women. however, there is little research in this regard and consensus has not been reached in the literature. objectives this study aimed to investigate the association between dmpa injection and periodontal health in reproductive age women. m...

BACKGROUND Depot medroxyprogesterone acetate contraception is widely used in Navajo women, a high-risk population for diabetes mellitus. However, depot medroxyprogesterone may lead to weight gain and independently decrease insulin sensitivity. We studied the association between depot medroxyprogesterone and development of diabetes in Navajo women. METHODS We studied Navajo women aged 18 to 50...

The properties of the depot fats of animals depend, to some extent, upon the nature of the dietary fats. Thus it was shown by Anderson and Mendel (1) that feeding of highly unsaturated oils results in the deposition of a body fat of high iodine number, whereas the administration of “hard” fat in the diet leads to a decrease in the iodine number of the depot fats. Recently Longenecker and Hildit...

A 50-year-old male patient with comorbid human immunodeficiency virus developed a relapse of bipolar disorder after a switch from oral aripiprazole 10 mg/day to intramuscular aripiprazole depot 200 mg every 28 days plus oral aripiprazole 5 mg/day. The patient was concomitantly taking lopinavir, saquinavir, ritonavir, silybum marianum extract, and omeprazole. Only 1 week after the switch, the pa...

BACKGROUND Nonadherence with antipsychotic medication is an important clinical and economic problem in the treatment of schizophrenia. This study identified treatment patterns and clinical characteristics that immediately precede the initiation of depot typical antipsychotics in the usual treatment of schizophrenia patients with a recent history of nonadherence with oral antipsychotic regimens....

Glucocorticoids promote fat accumulation in visceral compared to subcutaneous depots, but the molecular mechanisms involved remain poorly understood. To identify long-term changes in gene expression that are differentially sensitive or responsive to glucocorticoids in these depots, paired samples of human omental (Om) and abdominal subcutaneous (Abdsc) adipose tissues obtained from obese women ...

Background Extracorporeal life support (ECLS) is widely used in refractory heart or lung failure, and the demand for inter-facility transportation on ECLS is expanding. However, little is known about post-transportation outcomes, the clinical safety of such transportation, or the characteristics of the transported patients. Methods This was a retrospective review of a 3-year, single-instituti...

In this paper we introduce a new class of Pickup and Delivery problems on circles (or rings). These arise in the field public transportation systems where autonomous (i.e. driverless) vehicles travel circular networks. We consider set stations arranged circle requests. Each request asks for certain quantity from pickup station to delivery station. A fleet capacitated is available at depot. firs...