نتایج جستجو برای: intensive therapy

تعداد نتایج: 770361  

Background Anti-N-methyl- d-aspartate receptor (anti-NMDAR) encephalitis is an autoimmune neurological disorder that usually occurs as a paraneoplastic syndrome and is particularly associated with ovarian teratoma. Standard therapy for severe cases is not established and the prognosis in patients who do not respond to first-line treatment is poor. Case Report An 11-year-old boy complained ps...

Journal: :International journal of occupational medicine and environmental health 2012
Katarzyna Kwiecień Maria Wujtewicz Wioletta Mędrzycka-Dąbrowska

Intensive care units and well-qualified medical staff are indispensable for the proper functioning of every hospital facility. Due to demographic changes and technological progress having extended the average life expectancy, the number of patients hospitalized in intensive care units increases every year [9,10]. Global shortages of nursing staff (including changes in their age structure) have ...

Journal: :The New England journal of medicine 2008
Frank M Brunkhorst Christoph Engel Frank Bloos Andreas Meier-Hellmann Max Ragaller Norbert Weiler Onnen Moerer Matthias Gruendling Michael Oppert Stefan Grond Derk Olthoff Ulrich Jaschinski Stefan John Rolf Rossaint Tobias Welte Martin Schaefer Peter Kern Evelyn Kuhnt Michael Kiehntopf Christiane Hartog Charles Natanson Markus Loeffler Konrad Reinhart

BACKGROUND The role of intensive insulin therapy in patients with severe sepsis is uncertain. Fluid resuscitation improves survival among patients with septic shock, but evidence is lacking to support the choice of either crystalloids or colloids. METHODS In a multicenter, two-by-two factorial trial, we randomly assigned patients with severe sepsis to receive either intensive insulin therapy ...

Journal: :Circulation 2009
Rodica Pop-Busui Phillip A Low Barbara H Waberski Catherine L Martin James W Albers Eva L Feldman Catherine Sommer Patricia A Cleary John M Lachin William H Herman

BACKGROUND The Epidemiology of Diabetes Interventions and Complications (EDIC) study, a prospective observational follow-up of the Diabetes Control and Complications Trial (DCCT) cohort, reported persistent benefit of prior intensive therapy on retinopathy and nephropathy in type 1 diabetes mellitus. We evaluated the effects of prior intensive insulin therapy on the prevalence and incidence of ...

2015
Yuan Liu Sui-xin Liu Ying Cai Kang-ling Xie Wen-liang Zhang Fan Zheng

[Purpose] To investigate the effects of combined aerobic and resistance training on glycolipid metabolism and inflammation levels in type 2 diabetes mellitus patients. [Subjects and Methods] Forty-two diabetes patients were randomized to the conventional therapy group (n = 20) or intensive therapy group (n = 22). The control group contained 20 healthy people. The conventional therapy group rece...

Journal: :The New England journal of medicine 2010
William C Cushman Gregory W Evans Robert P Byington David C Goff Richard H Grimm Jeffrey A Cutler Denise G Simons-Morton Jan N Basile Marshall A Corson Jeffrey L Probstfield Lois Katz Kevin A Peterson William T Friedewald John B Buse J Thomas Bigger Hertzel C Gerstein Faramarz Ismail-Beigi

BACKGROUND There is no evidence from randomized trials to support a strategy of lowering systolic blood pressure below 135 to 140 mm Hg in persons with type 2 diabetes mellitus. We investigated whether therapy targeting normal systolic pressure (i.e., <120 mm Hg) reduces major cardiovascular events in participants with type 2 diabetes at high risk for cardiovascular events. METHODS A total of...

2009
Stephan A. Mayer

In 2008, there were clinical trial advances in 3 areas that will impact on the way stroke care is practiced in the emergency department and intensive care unit (ICU). These include (1) the positive results of the European Cooperative Acute Stroke Study (ECASS) III trial, extending the time window for intravenous thrombolytic therapy for acute ischemic stroke; (2) the negative results of 2 trial...

2018
Philip M Bath Lisa J Woodhouse Jason P Appleton Maia Beridze Hanne Christensen Robert A Dineen Lelia Duley Timothy J England Katie Flaherty Diane Havard Stan Heptinstall Marilyn James Kailash Krishnan Hugh S Markus Alan A Montgomery Stuart J Pocock Marc Randall Annemarei Ranta Thompson G Robinson Polly Scutt Graham S Venables Nikola Sprigg L M Christensen L Bentsen C Krarup Hansen T T Thomsen C Kruuse H H Jensen S S Hansen V Petrovic N Beridze N Kakabadze T Kherkheulidze D Kakabadze I Toidze N Lobjanidze N Akiashvili A Tevdoradze N Khizanishvili T Tsanava R Taylor I Iniesta J Kok J Duignan M Funnell P Cariga M Rodriguez I J Watson S Tennant M Macleod J Furnace H Gow J Irvine A Joyson S Nelson V Taylor M Smith R Bellfield B Hairsine R Davies A Dodd J Corrigan M Doherty A Ahmed C Denniss S Johnson-Holland K A Kay R Icart Palau G Auld P Daboo R Erande G Grimwood D Hove L Howaniec O Redjep R Rangasamay G Butt D Sandler J Reddan S Stafford J McIlmoyle S Maguire P Murphy J Chambers L Guthrie M Osborn A Steele M Burn A Benford A Misra D Hilton E O'Brien E Amis S Finlay J Mitchell O Geraghty K Harvey B Hazel S Mashate P Wilding M Sajid M Ball R Gascoyne R Sivakumar A Wright K Chatterjee S Booth H Eccleson C Kelly S Leason C Perkins D Bruce E Brown S Clayton M Garside G Rogers E Lawrence S Mahmood C Watchurst D Chadha L Glover L Holford K Smith D Walstow R Williams L O'Shea J Goodsell C Athulathmudali E Barbon R Namushi P Jacob L Johnson D Morse C McGhee O Speirs S Atkinson A Peacocke P Langhorne R Graham F Wright C McAlpine A Ravindrane M Bajoriene L Matter S Windebank E Giallombardo D Dellafera C Eglinton J Wilson D Broughton K Chapman L Dixon M Zaidi K Ayes J Kessell D Manawadu O Adegbaju J Aeron-Thomas K Anderson A Brigden E Cattermole J Good S Hassan E Khoromana L Lee-Carbon K Marks E Mckenzie N Sikondari M Cooper K Whysall I Wynter J Bamford A Hassan P Wanklyn M Kambafwile L Makawa D Waugh E Veraque MGG Soliman S Arif R Brown S Butler C Hewitt J Hindle A Pusalkar H Beadle K Chan M Siddiqui P Dangri S Buddha A Asokanathan A Mistri D Eveson K Musarrat L Manning S Anand P Christian S Khan C Patel M Sein J Banns E Gibson T Gordon Y Gruenbeck S Wong P Datta G Bateman L Jackson A Needle Y Duodu R Oliver C Padilla-Harris M Barber D Esson F Brodie C McInnes K Fotherby D Butler D Morgan K Preece A Willberry M Dent F Hammonds J Hunt C Vernon D O'Kane F Faola P Lai J O'Callaghan C Smith C Price R Lakey V Riddell A Smith G Storey S Munshi A Buck J Clarke N Gilzeane M Godfrey R Keshvara C Richardson J Roffe L Ryan F Shelton W Sunman A Tittle J Tomlinson K Whittamore G Wilkes P Owusu-Agyei N Temple D Mangion A Hardwick K Netherton A Mohd Nor B Hyams S Norman N Persad S Ragab C Dickson J Dube E Jinks K Knops B Wadams K Ali J Gaylard G Spurling L Sztriha T Ajao M Alao F K Chan P Webster P Howard T J Dobson L Hyatt D Sims J Cunningham B Esisi T Cassidy M Bokhari B McClelland B Mokoena G Gunathilagan S Jones M Reader G Thomas S Tilby P Findlay F Barrett F Leslie S Ross I Shread J Okwera J Howe F Harrington G Courtauld C Schofield R Donnelly M Maddula J Scott J Beavan K Muhidden I Memon M Clarke A Hedstrom L Mills A Hemsley A Bowring L Boxall H Kingwell S Keenan C Roughan A Manoj P Cox G Fletcher P Lopez H Emsley B Gregary A McLoughlin S Raj C Roffe N Abano A Barry A Butler R Carpio K Castro K Finney S Gomm J Hiden J Grocott S Lyjko H Maguire A Remegoso R Sanyal S Stevens I Natarajan J Chembala G Muddegowda A Warusevitane A Blight O Balazikova C Lawlor L Shaw D Button D Howcroft S Lucas B Madigan S McCann A Dixit A Barkat J Davis M Fawcett L Finlay H Guy C Hays V Hogg E Horsley C Hubbuck C Pringle C Stevenson K Storey T Thompson S Woodward A Banerjee C Allcock S Merotra C Douglass E Campbell R Jarapa M Johnes C Keaveney T Marsden Z Naing J Perez K Shaw T Black A Anthony C Clarke J Paterson K Deighton E Temlett C Blank C Doyle S Duty K Gill K Harkness C Kamara E Richards K Elfandi P Guyler P Harman C Khuoge S Kunhunny S Tysoe B Moynihan T Adedoyin N Chopra N Dayal R Ghatala N Jeyaraj I Jones F Kennedy L Kerin N Khanom S Lewis S Maheswaran L Montague M Niemierko J O'Reilly S Trippier F Watson P Wilkinson E Young K Dizayee H Cochrane J O'Connell L Mokoena E Osborne A Nair J Greig C Jenkins J Powell F Price M Chowdhury S Brixey L Hunt N Rands G Rose S Stoddart M Srinivasan N Motherwell R Shekhar T Fuller A Lankester P Lingwood C Rankin H Webb B Jupp J Bell G Hann B Longland C Ovington B Bhaskaran G Ayres C Bailey H Bearne J Buxton P Fitzell C Hilaire D Kelly S Szabo D Tomlin E Gamble B Charles R Kumar T Fluskey Z Mellor J Peters V Sutton A Kenton I Martin S Nyabadza S Ghosh M Henry B Kumar C Ambulo S Crawford T Nozedar M Platton V Cvoro M Couser K McCormick D Wilkinson K Javaid S Hurdowar T Attygalle S Sundayi O Orugun H Crowther R Jolly U Poultney A Azim M Krasinska-Chavez J White N Sengupta J Margalef M G Metiu S Meenakshisundaram S Dealing D Hargroves E Beranova L Cowie H Rudenko A Thomson A Verrion K Rashed S Board C Buckley D Hayward

BACKGROUND Intensive antiplatelet therapy with three agents might be more effective than guideline treatment for preventing recurrent events in patients with acute cerebral ischaemia. We aimed to compare the safety and efficacy of intensive antiplatelet therapy (combined aspirin, clopidogrel, and dipyridamole) with that of guideline-based antiplatelet therapy. METHODS We did an international,...

Journal: :Stroke 2011
Todd H Wagner Albert C Lo Peter Peduzzi Dawn M Bravata Grant D Huang Hermano I Krebs Robert J Ringer Daniel G Federman Lorie G Richards Jodie K Haselkorn George F Wittenberg Bruce T Volpe Christopher T Bever Pamela W Duncan Andrew Siroka Peter D Guarino

BACKGROUND AND PURPOSE Stroke is a leading cause of disability. Rehabilitation robotics have been developed to aid in recovery after a stroke. This study determined the additional cost of robot-assisted therapy and tested its cost-effectiveness. METHODS We estimated the intervention costs and tracked participants' healthcare costs. We collected quality of life using the Stroke Impact Scale an...

2013
Hui Fan QingRong Pan Pengrui Zhang Jia Liu Yuan Xu Xinchun Yang

BACKGROUND It is difficult in clinical practice to differentiate patients with newly diagnosed diabetes and ketosis. The aim of this study was to investigate the effect of intensive insulin therapy on islet function in patients with new-onset diabetes and concomitant ketosis, and to determine the value of alternation in islet function in the typing of diabetes. MATERIAL/METHODS A total of 206...

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